Interneurons that fail to propagate electrical signals in mice that model Dravet syndrome may cause the animals, like people with the autism-linked condition, to die suddenly.

The experimental compound, called GSK-LSD1, enhances social preferences and reduces repetitive grooming in mice, according to a new study.

Together, the neurons are part of the corticostriatal circuit, which has been implicated in autism.

The animals recall fear more readily if a set of inhibitory neurons in the hippocampus is switched on.

Overexpressing genes involved in the pathway, which regulates protein quality, changes repetitive behaviors in the animals.

The machine-learning tool, which automatically counts how many marbles a mouse buries, appears to distinguish between hyperactivity and repetitive behaviors.

A brain area called the tail of the striatum may account for the shift.

The drug suppresses an overactive signaling pathway implicated in tuberous sclerosis complex.

The new animal line could accelerate the discovery of gene-activating therapies for the autism-linked condition Rett syndrome.

Given the known link between severe maternal infections and autism, some scientists are investigating whether COVID-19 during pregnancy can affect a child’s neurodevelopment.