Gene therapies and the factors influencing autism traits top Spectrum’s list of the 10 most notable research findings we covered in 2020.

Mice that model 22q11.2 deletion syndrome lack social memory, but that trait can be reversed using a drug that targets the flow of potassium ions in neurons.

Two types of neurons process social information, a new mouse study suggests, but only one is disrupted in mice missing the autism-linked gene FMR1.

Spectrum is covering the 2020 International SYNGAP1 Scientific Conference, which took place virtually because of the coronavirus pandemic. Here we’re highlighting researchers’ reactions to noteworthy presentations.

Mice with mutations in the autism-linked gene SYNGAP1 have trouble sensing touch, which may stem in part from brain-circuit alterations and dulled alertness.

A gene-editing treatment shows long-lasting effects in a mouse model of Angelman syndrome, a genetic condition related to autism.

A tool that relies on video cameras and machine learning can identify mice that have mutations in a top autism gene by their behaviors. It also detects how a widely used autism drug affects their movements.

Mice missing an autism gene groom themselves more than usual and have altered circadian rhythms after nighttime exposure to light.

A new treatment curbs deadly seizures in a mouse model of Dravet syndrome, a severe form of epilepsy.

Autistic people and their families are increasingly experimenting with marijuana to try to ease problems such as insomnia, epilepsy and chronic pain — and traits of autism. But there is little evidence for its safety or effectiveness.