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Spectrum: Autism Research News

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Subtyping autism using fMRI: A quick take at SfN with Marco Pagani

Pagani used mouse models to connect autism etiologies to brain connectivity alterations and then found similar alterations in people with idiopathic forms of the condition.


Screening zebrafish autism models: A quick take at SfN with Ellen Hoffman

Zebrafish with mutations in 10 different autism-linked genes show a range of unique and shared phenotypes.


Tying PPFIA3 to autism: A quick take at SfN with Tuan Chao and Maimuna Paul

Work in fruit flies has helped Paul decode a neurodevelopmental syndrome in children caused by rare de novo variants in the gene PPFIA3.


Decoding sensory brain networks: A quick take at SfN with Ethan Scott

Scott describes his work on sound processing differences in the brains of zebrafish that model fragile X syndrome.


Novel protocol captures autism voices across the spectrum

Interview techniques that cater to a range of communication abilities can elicit the perspectives of autistic youth with cognitive and verbal challenges.


Switching neurons on and off to probe autism circuits

A 3D optogenetics method can mimic natural rhythms of neural activity, rendering previously unanswerable questions amenable to inquiry — including questions about autism.


Mitochondria: An energy explanation for autism

People with autism have more mutations than others do in both mitochondrial DNA and nuclear DNA that affects mitochondrial function.


Video: Wearable sensors pick up early signs of autism

Audio and motion-sensor recordings offer a remote window into a baby’s first years and make it easier for families to participate in research.


Huda Zoghbi: Taking genetic inquiry to the next level

Over the course of a career spanning more than three decades, Huda Zoghbi has won almost every major biology and neuroscience research award that exists. More than 20 years since she discovered the gene behind Rett syndrome, she remains laser focused on unlocking the condition’s secrets and finding effective treatments.


The gut’s connection to autism

Autistic children are up to four times as likely as their non-autistic peers to have digestive problems, and several small studies show they may also have atypical microbial communities living in their guts.