A new tool enables researchers to create mosaic mutations in only some cells and then accurately identify which cells are affected.
Spectrum: Autism Research News
Tag: mouse models
A glowing protein tracks serotonin levels and location in the brains of living mice and could yield clues to the neurotransmitter’s role in autism.
A Hollywood-inspired video tool that captures movement in three dimensions over extended time periods shows that rats lacking the autism-linked gene FMR1 have different grooming patterns than controls do.
On 10 February, André Fenton spoke about rethinking dysfunction in fragile X model mice.
Mice missing a copy of MAGEL2 have trouble discerning between a familiar mouse and an unfamiliar one; treating them with the social hormone vasopressin reverses this deficit.
Mutations in the autism-linked gene DNMT3A lead to the behaviors and gene-expression changes seen in different neurodevelopmental conditions.
Sleep disruption early in life has long-lasting consequences for mice missing a copy of the autism-linked gene SHANK3.
Female mice missing a copy of the autism-linked gene MECP2 in a specific set of inhibitory neurons have a hard time heeding pups’ calls and herding litters.
Sensory problems in people with fragile X syndrome may stem from hyperactive neurons, a mouse model study suggests.
People and mice with only one working copy of the autism gene SYNGAP1 may have trouble processing sights and sounds.