Tag: mouse models

September 2017
News

Monkey model reveals new role for top autism gene

by  /  11 September 2017

Monkeys missing the gene SHANK3 have too few neurons in the prefrontal cortex, a brain region involved in planning and social behavior.

1 Comment
August 2017
Week of AugustAug
14th
2017
News / Spotted

Transcranial treatment; maternal inflammation; autism ants and more

by  /  18 August 2017

Transcranial treatment may bolster memory in adults with autism, inflammatory molecule may alter an emotional brain region in newborns, and examining ants could yield insights into autism

0 Comments
News / Toolbox

Spheres of cells reveal which drugs can enter brains

by  /  18 August 2017

Microscopic balls of brain and blood vessel cells mimic the barrier that protects the brain from foreign invaders.

0 Comments
News

Social interactions shape gene expression in fragile X mice

by  /  16 August 2017

Mice missing FMR1, the gene mutated in fragile X syndrome, have an atypical brain response to meeting an unfamiliar mouse.

0 Comments
Week of AugustAug
7th
2017
News / Spotted

Off-key outcomes; visualizing variants; urine indifference and more

by  /  11 August 2017

Music therapy proves ineffective for autism, brain structures differ with 16p11.2 duplications and deletions, and mice missing NLGN3 may influence the sociability of their littermates.

2 Comments
News

Mice made with CRISPR usher in new era of autism research

by  /  7 August 2017

Researchers have debuted two mouse models of autism made using the gene-editing tool CRISPR. Both strains lack one copy of CHD8, a gene with strong ties to autism.

0 Comments
News / Toolbox

Innovative tool allows for virtual experiments on mouse brain

by  /  4 August 2017

New software transforms mouse brain scans into a virtual brain that scientists can manipulate.

0 Comments
News

Flash of light shifts social behavior in autism mice

by  /  2 August 2017

Turning on a set of neurons that dampen brain activity improves social behavior in a mouse model of autism; turning off neurons that excite brain activity does the same thing.

2 Comments
July 2017
News

Anxiety, seizures mark mice with extra copy of autism gene

by  /  31 July 2017

Mice with an extra copy of UBE3A, a gene linked to autism, have learning problems and anxiety, and are prone to seizures and fine-motor problems.

0 Comments
News

Antidepressant eases some autism features in mice

by  /  28 July 2017

A drug that keeps neurons bathed in the chemical messenger serotonin prevents social abnormalities in a mouse model of dup15q syndrome.

0 Comments
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