A new wiring diagram of the mouse brain could help autism researchers better study how brain connections vary in mice with different genetic backgrounds.

Treatments for Rett syndrome that aim to boost levels of the protein MECP2 may not help everyone with the condition.

Mice missing one copy of the autism-linked gene DDX3X have smaller brains and worse motor skills than mice with both copies of the gene, according to a new unpublished study.

Deleting the autism-linked gene CNTNAP2 from mice leads to distinct cellular and electrical changes in the cerebellum, according to two unpublished studies presented virtually today at the 2021 Society for Neuroscience Global Connectome.

Mice missing a copy of the autism-linked gene PTEN show a reduced preference for social interaction, possibly due to atypically large, overconnected dopamine neurons. Easing the overconnection may alleviate this trait.

A novel microscopy technique offers the most detailed look to date at the proteins present at neuronal junctions.

Mutations in the autism-linked gene ASH1L change how neurons grow and develop.

Even when they share identical genetic backgrounds, mice from separate litters show different patterns of development, according to a new study.

A set of neurons connecting the prefrontal cortex and the thalamus helps regulate social interactions in mice.

Mutations in POGZ, a gene strongly linked to autism, lead to a signaling imbalance in multiple brain regions in mice, according to two new studies.