The findings put genetic background forward to help explain autism’s heterogeneity.
Spectrum: Autism Research News
Tag: mouse models
Cells from people with fragile X syndrome overproduce — but don’t accumulate — proteins. New work suggests that excessive protein breakdown may account for this discrepancy, and explain some of the syndrome’s traits.
The people-focused researcher shares her secrets to carving out time for grant writing, creating work-life balance and letting go of unread emails.
Memories from Diering’s life trace the rising star’s scientific path from raising lizards as a child and later exploring home brewing to heading a lab that investigates memory, sleep disturbances and early development in animals with autism-linked mutations.
A new gene therapy approach for epilepsy tamps down neural activity on demand.
Rumbaugh, who studies how the autism-linked gene SYNGAP1 shapes brain development, describes how he has embraced coastal living and which aspects of his career he wouldn’t do over.
Having an infection during pregnancy is tied to a small increase in the chances of having an autistic child, but the connection may not be causal.
The in-depth approach shows mutations in the autism-linked gene disrupt neuronal growth and communication, as well as mitochondrial gene expression.
Using imaging methods to sort mouse models of autism may help identify subtypes of autistic people with similar underlying biology.