Mice and people missing a copy of a chromosomal region called 16p11.2 show similar patterns of weak brain connections.

Mice with one inactivated copy of CHD8, a top autism gene, show an unusually high degree of synchrony in neural activity between brain regions.

Female mice may compensate for the loss of a piece of chromosome 16 better than male mice do.

The gene-editing tool CRISPR may cause thousands of off-target mutations, but critics say it’s way too soon to accuse it of infidelity.

Boosting the activity of a class of neurons that dampen brain signals eases social problems in a mouse model of autism.

Mice lacking CNTNAP2, a gene strongly linked to autism, are acutely sensitive to pain.

Mice missing TAOK2, a gene in a segment of chromosome 16 linked to autism, have big brains, immature neuronal junctions and asocial behavior.

Deleting one copy of a gene called MVP impairs the brain's ability to adapt to changes in the environment.