Tag: mouse models

February 2020
brain form in the shape of white flowers on black background with the striatum in red
News

Striatum, the brain’s reward hub, may drive core autism traits

by  /  17 February 2020

Associated primarily with its role in movement, the striatum may also influence the social difficulties of autistic people.

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January 2020
neurons firing in black and white
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Brain organoids may shed light on seizures in Angelman syndrome

by  /  22 January 2020

The mutation that causes Angelman syndrome makes neurons hyperexcitable, which may explain the frequent seizures that most people with the syndrome have.

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December 2019
Features / Special Reports / 2019: Year in review

Notable papers in autism research in 2019

23 December 2019

This year’s top papers deepen our understanding of autism’s genetics and reveal mixed results from trials of autism therapies.

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Mother mouse with pups on white
News

Multiple genes may conspire to lead to autism traits

by  /  23 December 2019

The many genes implicated in Williams syndrome, a condition related to autism, may all work together to exert their effects on behavior.

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Mice neurons seen in green
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Loss of autism gene may lead to pile-up of proteins in neurons

by  /  19 December 2019

A shortage of CUL3, a leading autism gene, may impair social behavior in mice by ramping up protein production in neurons.

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Magnified view of mitochondria in mice
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Immune cells may underlie anxiety in autistic people

by  /  16 December 2019

Some cases of anxiety, which often accompanies autism, may stem from a faulty immune system, a new study suggests — but some experts are skeptical.

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A single ecstasy pill on a blue background.
News

Distinct brain pathway underlies ecstasy’s social effects

by  /  11 December 2019

The drug popularly known as ecstasy may boost sociability through brain circuits distinct from that underlying its ‘high.’

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red blood cells
News

Gene repeats tied to autism may prevent anemia

by  /  9 December 2019

Extra copies of a gene called BOLA2 predispose people to autism and may protect against iron deficiency.

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November 2019
News

Drug combination mutes sensitivity to noise in autism mice

by  /  25 November 2019

A mix of two drugs eases hypersensitivity to noise in mice missing an autism gene — offering the promise of a similar treatment for autistic people.

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News

Mouse study reveals overlooked target for autism therapies

by  /  20 November 2019

Blocking one form of an enzyme implicated in autism eases unusual behaviors and seizures in mice missing a top autism gene.

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