Skip to main content

TOPIC

Genes

Rare or common, inherited or spontaneous, mutations form the core of autism risk.

October 2020
Brain hemispheres color-coded.
News

Autism shares brain structure changes with other psychiatric conditions

by  /  1 October 2020

Atypical development of a particular type of neuron explains the structural similarities seen in the brains of people with autism, schizophrenia and other conditions, according to a new study.

0 Comments
September 2020
Illustration shows two long rows of vials with genetic information inside, the shadows they cast are in the shape of humans.
Features / Deep Dive

How scientists secure the data driving autism research

by  /  30 September 2020

Protecting the privacy of autistic people and their families faces new challenges in the era of big data.

0 Comments
White lab mouse sitting in a gloved hand.
News

Silencing ‘poison exon’ eliminates deadly seizures in mice

by  /  24 September 2020

A new treatment curbs deadly seizures in a mouse model of Dravet syndrome, a severe form of epilepsy.

0 Comments
Micrograph of a mitochondria.
News

Fragile X syndrome traits may stem from leaky mitochondria

by  /  11 September 2020

Plugging a leaky mitochondrial membrane may help fragile X neurons to mature and function more efficiently.

0 Comments
Colorful chart showing variants in chromosomes.
News

Scan of genomes for inherited variants lays bare new autism candidate

by  /  10 September 2020

Lowered expression of a gene called DDHD2 may increase a person’s likelihood of having autism, according to a new analysis.

0 Comments
Neurons in a macaque cortex express parvalbumin in red.
News / Toolbox

Virus-based method manipulates inhibitory neurons in brains

by  /  9 September 2020

A new viral tool can selectively control different types of neurons that dampen brain activity in rodents, monkeys and people.

0 Comments
DNA helix inside the human body
News

Autism genetics, explained

by  /  3 September 2020

The more scientists dig into DNA, the more intricate its contribution to autism seems to be. Here, we unravel the complex genetics of autism.

1 Comment
Zebrafish embryos with various deformities.
News / Toolbox

CRISPR technique knocks down gene expression in animal embryos

by  /  2 September 2020

A new method that suppresses gene expression in the embryos of fish and mice may help researchers study autism genes in early development.

0 Comments
August 2020
Two mice side-by-side.
News

Drug improves social behaviors, oxytocin signaling in autism mouse model

by  /  31 August 2020

Mice missing the autism gene NLGN3 have altered social behaviors and brain responses to the hormone oxytocin, both of which improve after treatment with a drug that helps regulate protein production.

0 Comments
Series of micrographs showing neurons with Rett syndrome mutations lacking liquid compartments around DNA.
News

DNA droplets may be key to Rett syndrome, researchers say

by  /  27 August 2020

Mutations in the MECP2 gene, which are associated with autism and Rett syndrome, interfere with a cell’s ability to form droplets of DNA that silence gene expression.

0 Comments