Mice lacking one copy of a gene called DDX3X have developmental delay and sensory, motor and behavioral problems — similar to those seen in people with a mutation in the gene.
Rare or common, inherited or spontaneous, mutations form the core of autism risk.
Turning down the expression of a gene linked to autism leaves zebra finches singing disorganized songs.
Researchers have used the gene-editing tool CRISPR to disable the MECP2 gene in marmoset embryos. The six such marmosets created seem to recapitulate aspects of Rett syndrome.
Researchers have used a new gene-editing technique to delete a segment of DNA associated with autism and schizophrenia from mouse brain cells.
Advances in research and help from families have brought scientists to the brink of an effective therapy for Angelman syndrome.
Deleting an autism gene called TRIO derails neurons’ journey to their destination.
A new autism mouse model carries the same mutation in a gene called ADNP that is seen in autistic people.
Researchers have identified mutations within regulatory regions that are likely to contribute to autism, using a speedy system of DNA ‘barcodes.’
Exposure to infection in utero may speed up the expression of many genes linked to autism — and hasten changes in brain anatomy.