TOPIC

Genes

Rare or common, inherited or spontaneous, mutations form the core of autism risk.

December 2018
News

Colombian cluster of fragile X may reveal insights into ‘premutation’

by  /  20 December 2018

Carriers of fragile X premutations in Ricaurte, Colombia, have more medical problems than carriers living elsewhere — and discovering why might yield treatments for the syndrome.

0 Comments
News

Massive analysis refines map of autism’s genetic roots

by  /  19 December 2018

The largest genetic analysis of postmortem brain tissue to date has yielded maps of when and where genes related to autism are turned on and off throughout life.

0 Comments
News

Analysis spotlights mutations in ‘dark’ regions of the genome

by  /  14 December 2018

Whole-genome scans of nearly 8,000 people link autism to spontaneous mutations in the stretches of DNA that regulate genes.

0 Comments
microsopy of human sperm
News

Study suggests Rett syndrome doesn’t always arise spontaneously

by  /  13 December 2018

Nearly one in four men who have a daughter with Rett syndrome carry mutations linked to the condition in some of their sperm.

0 Comments
Multimedia / Webinars

Webinar: Patricia Braga discusses stem-cell models of autism

12 December 2018

Watch the complete replay of Patricia Braga describing studies of autism involving stem cells.

0 Comments
Microscopic view of spermatozoa
News

Some autism mutations go undetected, new study suggests

by  /  5 December 2018

Some mutations that contribute to autism and arise spontaneously may be mistaken for inherited mutations.

0 Comments
November 2018
Large group of different lab mice: white mice, black and white mice and light brown mice, all in a cage on wood chips.
News / Toolbox

Database compares protein function across dozens of mouse strains

by  /  23 November 2018

A new resource details the protein-coding portions of the genomes of 36 popular mouse strains.

0 Comments
News

Top autism gene may rewire brain by altering expression of other genes

by  /  15 November 2018

The autism gene TBR1 controls the expression of several other candidate genes that govern the architecture of the brain’s outer section.

0 Comments
RNA sequences in yellow and blue.
News / Toolbox

Tool analyzes mysterious set of RNAs for clues to function

by  /  9 November 2018

A software tool finds possible functions for long RNA molecules that aren’t transcribed into proteins.

0 Comments
News

Gene expression ‘barcode’ maps cells in brain tissue

by  /  7 November 2018

A new technique transforms the previous broad-brush picture of a brain region into a pointillist masterpiece of neuronal subpopulations associated with specific activities.

0 Comments