Genes

New results implicate an enzyme called ERK in the consequences of missing a segment of chromosome 16.

Over the past year, HNRNPU, a gene well known for its link to epilepsy, has emerged as a new autism candidate.

A new tool can predict a genetic problem called ‘haploinsufficiency’ in which a mutation impairs the function of one copy of a gene.

About 10 percent of people with a large mutation in chromosome 22 have autism, attention deficit hyperactivity disorder or intellectual disability.

A new method enables researchers to assess the biological impact of thousands of subtle mutations.

A miniature particle delivers the gene-editing tool CRISPR into the brains of fragile X mice.

Rats with a mutation in CACNA1C, a gene linked to autism, make fewer happy squeaks while playing than controls do, and ignore other rats’ requests to play.

Four new techniques expand the repertoire of the gene editor CRISPR.

Mice with a mutation in a top autism gene may have altered levels of certain gut bacteria; feeding the mice one of these bacterial species eases some of their troubles.

People with mutations in SHANK3 have milder features than do those missing a chunk of DNA that includes the gene.