Genes

People with particularly low levels of FMRP, the protein lacking in those with fragile X syndrome, are more likely to also have autism and severe intellectual disability.

An atlas that details gene expression in neurons and other cells from the intestines of mice and people may help to elucidate the link between gut problems and autism.

Autistic children’s traits track with subtle, autism-like behaviors in their mothers; women with these traits may also carry a genetic predisposition to the condition.

Neurons derived from people with 22q11.2 deletion syndrome show deficits in calcium signaling and electrical activity, pointing to possible therapeutic targets.

Mice missing an autism gene groom themselves more than usual and have altered circadian rhythms after nighttime exposure to light.

Atypical development of a particular type of neuron explains the structural similarities seen in the brains of people with autism, schizophrenia and other conditions, according to a new study.

A new treatment curbs deadly seizures in a mouse model of Dravet syndrome, a severe form of epilepsy.

Plugging a leaky mitochondrial membrane may help fragile X neurons to mature and function more efficiently.