TOPIC

Genes

Rare or common, inherited or spontaneous, mutations form the core of autism risk.

August 2018
News

Blocking key enzyme eases memory problems, anxiety in autism mice

by  /  1 August 2018

New results implicate an enzyme called ERK in the consequences of missing a segment of chromosome 16.

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July 2018
News

Studies unveil hidden ties between epilepsy gene and autism

by  /  23 July 2018

Over the past year, HNRNPU, a gene well known for its link to epilepsy, has emerged as a new autism candidate.

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A red and blue pattern of genes.
News / Toolbox

Algorithm flags harmful mutations in single copies of genes

by  /  20 July 2018

A new tool can predict a genetic problem called ‘haploinsufficiency’ in which a mutation impairs the function of one copy of a gene.

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News

Mutations in chromosome 22 bring big risks, but only for some

by  /  16 July 2018

About 10 percent of people with a large mutation in chromosome 22 have autism, attention deficit hyperactivity disorder or intellectual disability.

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News

New approach predicts impact of mild mutations in autism

by  /  11 July 2018

A new method enables researchers to assess the biological impact of thousands of subtle mutations.

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a particle of gold and a protective shell nable CRISPR to traverse safely into the brain.
News

Gene editing via nanoparticles may treat autism syndromes

by  /  5 July 2018

A miniature particle delivers the gene-editing tool CRISPR into the brains of fragile X mice.

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News

Rat squeaks may reveal autism gene’s role in communication

by  /  2 July 2018

Rats with a mutation in CACNA1C, a gene linked to autism, make fewer happy squeaks while playing than controls do, and ignore other rats’ requests to play.

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June 2018
tangles of brightly colored RNA, DNA and enzymes
News / Toolbox

Refined versions of gene-editing tool increase its versatility

by  /  29 June 2018

Four new techniques expand the repertoire of the gene editor CRISPR.

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Scanning electron micrograph (SEM) of Lactobacillus reuteri. Lactobacillus reuteri, a probiotic bacterium, is found in breast milk and the human gastrointestinal tract. It is also found in cattle, pigs, chickens, turkeys, mice, hamsters, gerbils, ostriches and rats. This Lactobacillus produces reuterin which suppresses pathogens in the guts.
News

Autism mutation alters balance of gut bacteria in mice

by  /  28 June 2018

Mice with a mutation in a top autism gene may have altered levels of certain gut bacteria; feeding the mice one of these bacterial species eases some of their troubles.

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News

Mutations in autism gene may trigger milder effects than does its loss

by  /  20 June 2018

People with mutations in SHANK3 have milder features than do those missing a chunk of DNA that includes the gene.

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