Mice missing a copy of the gene SENP1 have atypical social behavior likely due to a signaling imbalance in the retrosplenial cortex.
Spectrum: Autism Research News
Rare or common, inherited or spontaneous, mutations form the core of autism risk.
Many genes linked to autism are switched on in the brain’s glia, cells that help neurons develop and synapses form.
An online database called NyuWa catalogs genetic variations among nearly 3,000 individuals and provides a comprehensive reference genome for the Han people.
Deleting a copy of the gene TBX1 depletes the fatty myelin insulation that surrounds neurons and reduces cognitive speed in mice.
Genes that appear to play a role in some birds’ ability to learn songs are frequently mutated in autistic people.
Rare variants that alter the expression of genes in the brain contribute to autism in people who also have a rare autism-linked mutation, according to a new study.
Two new methods make it possible to delete long sections of the genome, expanding the reach of CRISPR gene editing.
A MECP2 gene therapy for Rett syndrome eases repetitive behaviors, anxiety and hyperactivity in a mouse model of Pitt-Hopkins syndrome.
These short reports from Spectrum journalists highlight some of the autism-related findings that caught our attention at the meeting this past week.