TOPIC

Genes

Rare or common, inherited or spontaneous, mutations form the core of autism risk.

November 2017
brain cells and microglia
News

Map of microglia in mouse brain may reveal role in autism

by  /  15 November 2017

Researchers have mapped how immune cells in the brain called microglia change with age in mice.

1 Comment
ett syndrome drugs are unlikely to affect all neurons in the brain in the same way.
News

Rett syndrome mutation’s effects vary by cell type

by  /  14 November 2017

Mutations in the Rett syndrome gene MECP2 have different effects on subtypes of neurons.

0 Comments
Organoids derived from fetal bone recapitulate brain development over the first 16 weeks of gestation.
News

‘Mini-brains’ mirror fetal brain development

by  /  14 November 2017

Spheres of brain cells derived from a fetal skull have gene expression patterns similar to those in brain tissue from the same fetus.

0 Comments
Opinion / Viewpoint

Electronic glow may disrupt sleep for people on the spectrum

by  /  13 November 2017

Exposure to certain types of light at night may exacerbate sleep issues among people with autism.

0 Comments
closed eye and wide open eye against sky
News

Autism may disrupt the body’s circadian clock

by  /  13 November 2017

Sleep problems in autism may stem from the same biological changes that underlie the core features of the condition.

0 Comments
spotlight on brain in doctor's office
News

Note to autism scientists: Control for z’s

by  /  13 November 2017

Differences in sleep and circadian rhythm may distort the results of autism studies.

1 Comment
lab mice
News

Fragile X behaviors may stem from gene’s loss in specific cells

by  /  13 November 2017

Deleting FMR1, the gene mutated in fragile X syndrome, in subsets of mouse neurons leads to distinct features of the condition.

0 Comments
Stem cells derived from an individual’s skin can become neurons with her unique genetic makeup.
News

Brain cells spun from skin point to subtypes of autism

by  /  12 November 2017

Neurons derived from people with a syndromic form of autism look and behave differently than do those from people with classic autism.

1 Comment
Genes that regulate brain activity in people with autism (right) differ from those in controls (left).
News

Distinct set of genes controls brain activity in people with autism

by  /  12 November 2017

A different set of genes regulates brain activity in people with autism than the set involved in controls.

1 Comment
Mice that lack UBE3A only in their inhibitory neurons are particularly susceptible to seizures.
News

Gene therapy technique prevents seizures in Angelman mice

by  /  12 November 2017

Introducing the gene UBE3A into neurons that dampen brain activity prevents seizures in a mouse model of Angelman syndrome.

0 Comments
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