Mutations in a gene called ADNP lead to a syndrome that includes autism, intellectual disability and problems with the gut, eyesight, heart and brain.

The gene-editing tool CRISPR may cause thousands of off-target mutations, but critics say it’s way too soon to accuse it of infidelity.

Two new online resources help researchers predict how mutations alter protein structure.

A new analysis of the genomes of more than 11,000 people reveals regions that have few mutations, indicating they have important functions.

Some children with autism inherit rare mutations in noncoding DNA from their unaffected fathers.

Some genes associated with autism may influence the thickness of the cerebral cortex, the brain’s outer layer.

Mice lacking CNTNAP2, a gene strongly linked to autism, are acutely sensitive to pain.

Genetic variants that affect mitochondria, the organelles that power cells, may increase the risk of autism.

Mice missing TAOK2, a gene in a segment of chromosome 16 linked to autism, have big brains, immature neuronal junctions and asocial behavior.