Genes

Researchers have uncovered more than 1,200 new protein-protein interactions involving proteins coded for by autism-linked genes.

Children with autism traits tend to show agitation, excitability, decreased sleep and other mild signs of mania in adolescence; the association is higher in identical twins than fraternal twins, suggesting that genetics plays a role.

Many genes linked to autism, schizophrenia and neurodevelopmental delay regulate gene expression and support communication between neurons.

Activity patterns of neuronal networks link different genetic subtypes of autism that have similar traits, according to new unpublished research.

The largest-yet study of genetic data from autistic people has identified 255 genes associated with the condition.

Researchers have rated more than 17,000 genes, including many linked to autism and other neuropsychiatric conditions, according to their sensitivity to deletions and duplications.

A novel method to evaluate the strength of the evidence linking autism to specific genes could reveal which ones are most useful to screen for.

Deleting CHD8 from the intestines induces gastrointestinal and behavioral changes in mice that resemble traits in people with mutations in the gene.

The investigational drug arbaclofen may right an imbalance between inhibitory and excitatory signaling in the animals’ brains.

Girls and women with mutations in the autism-linked gene DDX3X may be particularly vulnerable to anxiety and self-harm.