Skip to main content

TOPIC

Genes

Rare or common, inherited or spontaneous, mutations form the core of autism risk.

June 2020
News

Study links gene to inherited form of autism

by  /  25 June 2020

Mutations in both copies of a gene called ACTL6B lead to autism, epilepsy and intellectual disability.

0 Comments
A genome data set shows colorful clusters by ancestry
News / Toolbox

Massive genomic database helps decode mutations’ effects

by  /  24 June 2020

A trove of DNA sequences from 141,456 people — and counting — offers an unparalleled look at genetic variation.

0 Comments
News

Decade of data dents idea of a ‘female protective effect’

by  /  12 June 2020

Brothers and sisters of people with autism are both about two to three times more likely than the general population to have an autistic child themselves.

0 Comments
May 2020
News

Reversing SHANK3 mutations in mice mitigates autism-like traits

by  /  28 May 2020

Correcting an autism gene mutation in fetal mice lessens some autism-like behaviors after birth.

0 Comments
News

Rare mutations in autism genes tied to intellectual disability

by  /  22 May 2020

A new study highlights the challenge of distinguishing genetic variants linked to autism from those associated with cognitive development.

0 Comments
News

Environmental factors unlikely to account for rise in autism prevalence

by  /  18 May 2020

The relative contributions of genetic and environmental factors to autism have held steady over multiple decades, according to a large twin study.

0 Comments
Human brain with prefrontal cortex highlighted.
News

DNA differences may shape gene expression in the brain before birth

by  /  7 May 2020

Many genes in a brain region implicated in autism change expression patterns in late fetal development, depending on differences in neighboring DNA.

0 Comments
April 2020
Two neuron images compared side by side
News

Lithium may treat behavior linked to autism gene

by  /  24 April 2020

The mood-stabilizing drug lithium seems to ease repetitive behaviors seen in mice missing SHANK3, an autism gene.

0 Comments
White mouse grooming
News

Gene linked to schizophrenia tied to autism-like behaviors

by  /  23 April 2020

Mice missing DLG2, a protein central to neuronal activity, are anxious, sleep poorly and overgroom themselves.

0 Comments
News / Toolbox

New atlas maps gene expression throughout the brain

by  /  22 April 2020

A comprehensive atlas of gene expression by brain region could spur new research on autism.

0 Comments