Genes

Researchers expand on the already enormous progress made on the Human Proteome Project

Many people with mutations in the NCKAP1 gene have autism or autism traits, according to a new study spanning seven countries.

A new study pinpoints the genes and cell types that may underlie the atypical brain structure seen in people with genetic conditions linked to autism.

Researchers expand a massive repository of data on gene activity in people to show differences between males and females.

People who have large mutations associated with autism and schizophrenia share atypical patterns of brain connectivity, according to a new study, especially between areas that process sensory information.

Mutations in a top autism gene called SYNGAP1 slow the rate at which zebrafish digest food and pass waste, and may also disrupt gut function in people.

Autism with intellectual disability is less heritable than autism alone, according to a new study of how the conditions run in extended families.

A gene-editing treatment shows long-lasting effects in a mouse model of Angelman syndrome, a genetic condition related to autism.

All five participants in a clinical trial of a gene therapy for Angelman syndrome experienced leg weakness, leading sponsors to pause the study.

The first genetic analysis of multiple types of variants from people with autism or other neurodevelopmental conditions reveals hundreds of genes that may be linked to neurodevelopment.