Genes

Researchers have monitored the active genome in brain organoids over the course of nearly two years — and may find clues to autism’s roots.

Studies of Rett syndrome hint at genes, cells and brain circuits that may be involved in autism — and may pave the way to treatments for both conditions.

Deleting an autism gene called TRIO derails neurons’ journey to their destination.

A new autism mouse model carries the same mutation in a gene called ADNP that is seen in autistic people.

Researchers have identified mutations within regulatory regions that are likely to contribute to autism, using a speedy system of DNA ‘barcodes.’

Exposure to infection in utero may speed up the expression of many genes linked to autism — and hasten changes in brain anatomy.

Mouse models of two genetic conditions related to autism show abnormalities in their movement patterns.

Injecting cells called interneurons into the brains of a mouse model of autism restores typical social behavior. But the reason for this effect is a puzzle.

Injecting the gene-editing tool CRISPR into the brains of mice may reverse the effects of an autism mutation at any age.