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Genes

Rare or common, inherited or spontaneous, mutations form the core of autism risk.

July 2019
News

Family groups, researchers join forces to solve mysteries of autism gene

by  /  10 July 2019

Families of children with mutations in a gene called SYNGAP1 have spurred research into the effects of the mutations on people — and how to treat them.

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News / Toolbox

New approach aids search for genetic roots of complex conditions

by  /  5 July 2019

A new method enables researchers to test algorithms for spotting genes that contribute to a trait or condition.

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June 2019
children standing in a line, oldest to youngest
News

Timing of autism treatments may be key to their success

by  /  20 June 2019

The timing of treatment is crucial for conditions related to autism — and more so for some conditions than for others.

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Mouse neurons in a grid show differences
News

Autism mutation may disrupt brain structure by disabling mitochondria

by  /  13 June 2019

Mice that lack a segment of chromosome 22 — a mutation associated with autism — have unusually sparse connections between brain regions.

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Cells in a rat brain
News / Toolbox

CRISPR advances offer enhancements to gene-editing tool kit

by  /  7 June 2019

New versions of the DNA editor CRISPR enable scientists to turn off specific genes in rats, detect mutations in human tissue and delete segments of the genome.

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primordial soup of ancient genes and single celled organisms
Opinion / Viewpoint

Evolution of autism genes hints at their fundamental roles in body

by  /  4 June 2019

Genes associated with autism are ancient, and mutations in them have wide-ranging effects on the body, indicating their importance.

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May 2019
News

Gut microbes from autistic children may alter behavior in mice

by  /  30 May 2019

Mice colonized with gut microbes from some autistic boys show behaviors like those of the boys.

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Artists interpretation of machine learning and genes
News

Mutations between genes, long overlooked, may be key in autism

by  /  27 May 2019

Spontaneous mutations that occur between genes may be as important in autism as those within genes.

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Mouse hippocampus view
News / Toolbox

New method yields maps of gene expression in multiple dimensions

by  /  24 May 2019

An array of minute beads enables researchers to build precise maps of gene expression in the brain.

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Individual cells from the brains of autistic people show distinct gene-expression patterns, and are shown in different colors.
News

Analysis of single cells implicates set of neurons in autism

by  /  22 May 2019

A set of neurons involved in complex cognitive functions may play a central role in autism.

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