Genes

Mice missing the autism-linked gene SHANK3 use more neurons to engage in social behavior than control mice do, reflecting a more disorganized, less efficient brain signaling network.

A new spin on the classic CRISPR gene-editing tool can alter the genome’s chemical tags and suppress gene expression for months.

The high levels of serotonin seen in the blood of some autistic people have confounded scientists for more than half a century. Despite so little progress, some researchers refuse to give up.

Loss of the gene KMT5B stunts growth in male mice and leads to social difficulties in female mice, a new study suggests.

Atypical patterns of neuronal activity and gene expression in the striatum may characterize autism in girls, according to a new study.

Worms and zebrafish missing both copies of the gene CHD7 have disrupted cellular signaling, a dearth of inhibitory neurons and behavior changes — all of which are reversed by the stimulant drug ephedrine.

The more scientists dig into DNA, the more intricate its contribution to autism seems to be. Here, we unravel the complex genetics of autism.

About one-third of the HNRNP gene family’s 33 members may be associated with neurodevelopmental conditions, including autism.

An autism-linked mutation could make the brain grow unusually large by prompting cells to express a chemical signal better known for its connection to cancer.