New studies bolster the idea that zebrafish models can say something meaningful about social behavior in autism.
Spectrum: Autism Research News
Rare or common, inherited or spontaneous, mutations form the core of autism risk.
Zebrafish with mutations in 10 different autism-linked genes show a range of unique and shared phenotypes.
A range of presentations at Neuroscience 2022 tie atypical social behavior to trouble discriminating between odors in the animals.
Work in fruit flies has helped Paul decode a neurodevelopmental syndrome in children caused by rare de novo variants in the gene PPFIA3.
People with dup15q syndrome and those with idiopathic autism have similar patterns of altered gene expression in early brain development and later in life.
Data from two separate research teams suggest the cells are key to sensory hypersensitivity in fragile X syndrome.
The study also reveals a link between language development and common variants.
The gene, YTHDF2, has not previously been linked to autism.
The findings, based on Swedish national registry data, suggest a critical need to expand mental health services for autistic people.