TOPIC

Genes

Rare or common, inherited or spontaneous, mutations form the core of autism risk.

News
Image of many sperm in a mosaic-like pattern

Genetic tests of sperm may forecast odds of autism in children

by  /  16 January 2020
Some men who have an autistic child carry mutations linked to the condition only in their sperm.
News
Variants linked to multiple conditions, including autism, tend to appear in genes that influence brain development, as shown in this chart in blue and grey.

Autism may share inherited variants with other psychiatric conditions

by  /  13 January 2020
Some of the inherited variants implicated in autism also increase the odds of schizophrenia, bipolar disorder, depression or attention deficit hyperactivity disorder.
News / Toolbox
People from Asia have high genetic diversity due to historical mixing with many ethnic groups, represented here by different colors. Each horizontal strip includes one more geographical region than the strip above it.

Catalog of Asia’s genetic diversity may aid search for autism variants

by  /  10 January 2020
A new resource details the genetic diversity of people in Asia and may shed light on genetic conditions such as autism.
January 2020
News

Autism’s genetic drivers may differ by sex

by  /  9 January 2020

Autism may stem from a different — and larger — set of genetic mutations in women than it does in men.

0 Comments
Young man in textured space, environmental factors and genes swarm in and around him
Opinion / Viewpoint

Autism heritability: It probably does not mean what you think it means

by  /  7 January 2020

The question of autism’s heritability is compelling for researchers and laypeople alike, but many people in both groups misunderstand its definition.

0 Comments
Brain MRIs showing injured blood vessels
News

Study ties gene active in developing brain to autism

by  /  6 January 2020

Mutations in a gene called ZNF292 lead to a variety of developmental conditions, including autism and intellectual disability.

0 Comments
December 2019
Mother mouse with pups on white
News

Multiple genes may conspire to lead to autism traits

by  /  23 December 2019

The many genes implicated in Williams syndrome, a condition related to autism, may all work together to exert their effects on behavior.

0 Comments
Mice neurons seen in green
News

Loss of autism gene may lead to pile-up of proteins in neurons

by  /  19 December 2019

A shortage of CUL3, a leading autism gene, may impair social behavior in mice by ramping up protein production in neurons.

0 Comments
variants across the genome are shown in a wheel shaped visualization
News / Toolbox

New database catalogs variants in autism genes

by  /  13 December 2019

A new database cross-checks study participants to avoid double-counting variants linked to autism genes.

0 Comments
a young girl has her height measured by a woman
News

Top autism gene tied to unusual skull, skeletal growth

by  /  12 December 2019

People with mutations in CHD8, a top autism gene, tend to be tall and have large heads.

0 Comments
red blood cells
News

Gene repeats tied to autism may prevent anemia

by  /  9 December 2019

Extra copies of a gene called BOLA2 predispose people to autism and may protect against iron deficiency.

0 Comments
Large genome sequence in blues and purple
News / Toolbox

Human reference genome gains global diversity

by  /  6 December 2019

A new reference genome includes sequences collected from people around the globe, plugging major gaps in the current one.

0 Comments
November 2019
News / Toolbox

Study links large set of common genes to brain structure

by  /  29 November 2019

A new analysis of nearly 40,000 people pinpoints 48 genetic variants that may determine the volume of certain brain areas.

0 Comments