Genes

Injecting a virus toting snippets of RNA into the rodent brain enables researchers to express genes in specific neuron types.

David and Bernardo Sabatini, brothers born just a year and a half year apart, invent their way to answering big questions about autism.

The absence of several interacting genes may underlie the developmental problems seen in people missing a segment of chromosome 16.

New results implicate an enzyme called ERK in the consequences of missing a segment of chromosome 16.

Over the past year, HNRNPU, a gene well known for its link to epilepsy, has emerged as a new autism candidate.

A new tool can predict a genetic problem called ‘haploinsufficiency’ in which a mutation impairs the function of one copy of a gene.

About 10 percent of people with a large mutation in chromosome 22 have autism, attention deficit hyperactivity disorder or intellectual disability.

A new method enables researchers to assess the biological impact of thousands of subtle mutations.

A miniature particle delivers the gene-editing tool CRISPR into the brains of fragile X mice.