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November 2011

Researchers map genetic variation in mice

by  /  9 November 2011

Researchers have sequenced 17 laboratory mice and mapped 56.7 million single-base DNA variants in their genomes, according to a study published 15 September in Nature. A companion paper in the same issue identifies more than 700,000 structural variants, which are insertions, deletions or other modifications of DNA.

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Sequencing technique optimal for postmortem brains

by  /  2 November 2011

A technique for detecting gene expression that detects short RNA messages is better suited than traditional methods for analyzing postmortem brain tissue, according to a study published 10 September in BMC Genomics.

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October 2011

Narrower amygdala scans lead to cleaner results

by  /  26 October 2011

Researchers have defined anatomical boundaries that minimize errors in brain-imaging measures of the amygdala, a region involved in emotion processing.

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Stem cells pinpoint players in nerve cell development

by  /  19 October 2011

Stem cells reprogrammed to become neurons can provide a picture of gene expression in neurons that is traditionally available only from brain tissue.

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Easy-to-make solution turns brains transparent

by  /  12 October 2011

Three common laboratory chemicals are all scientists need to create see-through brains ideal for visualizing complex neural circuits.

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Researchers engineer light-responsive strains of mice

by  /  5 October 2011

Researchers have engineered four new mouse lines that each show activation of a different subset of neurons in response to a blue light.

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September 2011

Three-dimensional re-creation reveals dendrite shapes

by  /  28 September 2011

Researchers have created detailed three-dimensional reconstructions of the numerous complex branches of dendrites, the signal-receiving ends of neurons.

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Questionnaire distinguishes autism, developmental disability

by  /  21 September 2011

Researchers have optimized an early social screening questionnaire to distinguish autism from other developmental disabilities in preschool-aged children.

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Reference set for Prader-Willi, Angelman syndromes debuts

by  /  14 September 2011

Researchers have developed standard genetic reference samples that clinicians can use to diagnose Angelman and Prader-Willi syndromes, two disorders associated with the same chromosomal region.

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Functional imaging studies may be marred by head motion

by  /  7 September 2011

Even small head movements inside a brain scanner can affect results, according to a report published 23 July in Neuroimage.

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