Brain circuit map identifies local networks
Neurons that respond to the same stimuli are grouped into sub-networks that can quickly communicate with each other, according to a study published 10 April in Nature.
Emerging tools and techniques that may advance autism research.
Neurons that respond to the same stimuli are grouped into sub-networks that can quickly communicate with each other, according to a study published 10 April in Nature.
Researchers have taken skin cells from individuals with schizophrenia, bathed them in chemical cocktails and coaxed them to develop into neurons, according to a paper published 13 April in Nature.
Exosomes, the brain’s system for delivering and recycling molecules, can be manipulated to carry therapeutic fragments of RNA or DNA across the blood-brain barrier and into neurons. The ingenious new technique was published 20 March in Nature Biotechnology.
Researchers have mapped the architecture of a brain circuit active during vision in the cerebral cortex — a region involved in memory and planning — they reported 10 March in Nature.
By shining a beam of light on a single brain circuit, researchers can compel mice to overcome their natural fears and boldly explore a new space, according to a study published 9 March in Nature.
Researchers have extracted and sequenced DNA from 52 postmortem brains from the Autism Tissue Program, providing a resource to study mutations and gene expression differences in the brains of people with the disorder.
A new technique can pinpoint the precise location of individual proteins at a synapse — the junction between neurons — at high resolution in brain tissue, according to a study published 9 December in Neuron.
Researchers have identified nearly 1,500 proteins present in the postsynaptic density — a complex collection of proteins that enables quick and flexible signaling across the brain. The results were published 14 January in Nature Neuroscience.
A genetic database of autism genes, called Autism Database, or AutDB, details curated information for more than 200 mouse models of autism, according to a report in the January BMC Genomics.
A new technique allows researchers to watch the long-term effects of disease on the brain, according to a study published in the February Nature Medicine. The approach could help scientists study changes in the brain that result from neurological disorders such as autism.