Researchers have mapped the levels of tiny RNA fragments that regulate gene expression in specific brain regions and subtypes of neurons. The results were published 12 January in Neuron.
Spectrum: Autism Research News
Emerging tools and techniques that may advance autism research.
Researchers have charted the expression of more than 15,000 brain genes across 15 stages of development, spanning from 4 weeks post-conception to more than 60 years of age, they reported 27 October in Nature.
Dried spots of blood taken from infants at birth can help clinicians screen for fragile X syndrome in countries with limited resources, according to a study published 11 October in Genetic Testing and Molecular Biomarkers.
A new technique efficiently screens for compounds that enhance or inhibit the formation of synapses, the junctions between neurons, according to a study published 25 October in Nature Communications.
Regions of the genome that contain the same genetic variants on both copies of a chromosome are more likely to contain autism-associated genes than other parts of the genome, according to a study published 14 October in Human Genetics.
Researchers have derived neurons from stem cells to investigate mutations that lead to Rett and fragile X syndromes.
Researchers have engineered 20 mouse lines that allow them to manipulate genes in specific neuronal circuits. The resource, reported 22 September in Neuron, will allow researchers to better explore the role of interneurons, which dampen signals in the brain, in mouse models of autism.
Browse Articles by Topic
Signs & Symptoms
Science & Society