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Emerging tools and techniques that may advance autism research.

Neuron-specific virus overcomes barriers to brain-related gene therapy

by  /  14 January 2022

A new viral variant can deliver genes exclusively to the brain, overcoming a key hurdle in treating neurological conditions using gene therapy.

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January 2022

New method spotlights synaptic plasticity in living mice

by  /  5 January 2022

Mice that express a fluorescent synaptic receptor reveal the interactions between neurons in unprecedented detail.

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December 2021

Artificial intelligence system categorizes interactions between mice

by  /  17 December 2021

New software can automatically identify and quantify mouse social behavior from videos, saving researchers time.

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Nighttime crowded Shanghai street scene with illumination from electric and neon signs.

New resource tracks genetic variations in Han Chinese populations

by  /  9 December 2021

An online database called NyuWa catalogs genetic variations among nearly 3,000 individuals and provides a comprehensive reference genome for the Han people.

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November 2021

New gene-editing tools delete long stretches of DNA

by  /  17 November 2021

Two new methods make it possible to delete long sections of the genome, expanding the reach of CRISPR gene editing.

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October 2021

‘Light beads’ method images activity across the mouse brain

by  /  12 October 2021

The new technique can record hundreds of thousands of neurons firing nearly simultaneously across big swaths of brain tissue in living mice.

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Annimation of eye tracking application following the pupil in a man's eye.

Web app tracks pupil size in people, mice

by  /  8 October 2021

The app relies on artificial intelligence and could help researchers standardize studies of pupil differences in autistic people and in mouse models of autism.

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September 2021
Cells in the cerebral cortex.

Atlas maps gene activity, accessibility in developing brain

by  /  30 September 2021

A new resource profiles gene expression and the accessibility of DNA in single cells across the developing human cerebral cortex and may help scientists decipher the effects of noncoding mutations linked to autism.

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Person with documents and a green pen.

New screen assesses suicidality in autistic adults

by  /  22 September 2021

A short questionnaire created in consultation with autistic people is the first of its kind to accurately gauge suicidal thoughts and behaviors among adults on the spectrum.

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New method uses virus-like protein to package, deliver RNA

by  /  9 September 2021

A novel gene delivery system taps a protein found in people to encapsulate messenger RNA and transport it into cells.

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August 2021
Markov cluster showing protein interactions in mice.

Protein atlas doubles number of known interactions in mice

by  /  26 August 2021

Thousands of protein-protein interactions mapped in mice reveal how these networks shift across seven kinds of tissue.

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