The new technique can record hundreds of thousands of neurons firing nearly simultaneously across big swaths of brain tissue in living mice.
Spectrum: Autism Research News
Emerging tools and techniques that may advance autism research.
Two new methods make it possible to delete long sections of the genome, expanding the reach of CRISPR gene editing.
A new resource profiles gene expression and the accessibility of DNA in single cells across the developing human cerebral cortex and may help scientists decipher the effects of noncoding mutations linked to autism.
A short questionnaire created in consultation with autistic people is the first of its kind to accurately gauge suicidal thoughts and behaviors among adults on the spectrum.
A novel gene delivery system taps a protein found in people to encapsulate messenger RNA and transport it into cells.
Thousands of protein-protein interactions mapped in mice reveal how these networks shift across seven kinds of tissue.
The software compares gene expression in cells derived from organoids with a reference atlas of the developing mouse brain.
A new technique can reveal where thousands of neurons send their axons — and measure the cells’ RNA levels for dozens of genes at the same time — in the mouse brain. It could be used to profile neural circuits underlying autism.
Thanks to a new engineered protein for optogenetics experiments, researchers can stimulate neurons with less light than usual and avoid damaging brain tissue.
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