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Emerging tools and techniques that may advance autism research.

A set of 4 multicolored brain scans showing development of cortical surface area.

New mapping method reveals subtleties of brain development

by  /  21 September 2022

The machine-learning approach could help identify how brain structure differs between autistic and non-autistic infants, the researchers say.

Previous articles
August 2022
Illustration of two chromosomes with copy number variants.

‘Dosage sensitivity map’ predicts active ingredients in copy number variants

by  /  31 August 2022

The catalog of rare copy number variants tied to autism and other conditions could help researchers identify which genes account for the mutations’ effects.

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Illustration of a cassette tape with the tape replaced by a DNA double helix

‘Retro-Cascorder’ tracks gene-expression timing

by  /  19 August 2022

The new tool may help researchers reconstruct the sequence of biological events that underlie development.

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On the left hand side are several abstract and blurry red and blue blobs. On the right hand side are a series of red and blue dots.

Machine learning streamlines neuroimaging data analysis

by  /  15 August 2022

The method could boost reproducibility across brain imaging studies of autism.

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July 2022

New software flags autism rat model’s telltale squeaks

by  /  29 July 2022

By breaking rodent vocalizations into parts, TrackUSF distinguishes rats with mutations in the SHANK3 gene from their wildtype counterparts.

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Sequencing trick identifies brain cells affected by large autism-linked mutation

by  /  25 July 2022

The method, called Orgo-Seq, reveals that a deletion of genes on chromosome 16 increases the proportion of immature neurons and neural precursors in brain organoids derived from people with the mutation.

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New resource maps gene expression, regulation in neuron subtypes

by  /  1 July 2022

The catalog could help researchers understand the effects of autism-linked DNA variants that fall outside genes.

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June 2022

Unlocking the mitochondrial genome for autism research

by  /  1 June 2022

The DNA specific to mitochondria is difficult to access, but new methods place its secrets within reach.

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May 2022
Someone in a yellow shirt stands at a kitchen counter, watching a cooking video on a small tablet computer and following along.

Standard quality-of-life screener validated for autistic adults

by  /  24 May 2022

Researchers updated the tool’s scoring system to better align with the experiences of autistic people.

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3D rendering of a mouse brain showing axons coming from the prefrontal cortex in various colors.

New atlas maps neuronal wiring in mouse brain

by  /  3 May 2022

The ‘projectome’ charts axonal pathways between individual cells in the prefrontal cortex, a brain region implicated in autism.

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April 2022

Deep-learning tool tracks interacting animals in real time

by  /  27 April 2022

By coupling the tool — called SLEAP — with optogenetics, researchers can determine the neural circuits underlying social behaviors.

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