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Emerging tools and techniques that may advance autism research.

On the left hand side are several abstract and blurry red and blue blobs. On the right hand side are a series of red and blue dots.

Machine learning streamlines neuroimaging data analysis

by  /  15 August 2022

The method could boost reproducibility across brain imaging studies of autism.

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July 2022

New software flags autism rat model’s telltale squeaks

by  /  29 July 2022

By breaking rodent vocalizations into parts, TrackUSF distinguishes rats with mutations in the SHANK3 gene from their wildtype counterparts.

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Sequencing trick identifies brain cells affected by large autism-linked mutation

by  /  25 July 2022

The method, called Orgo-Seq, reveals that a deletion of genes on chromosome 16 increases the proportion of immature neurons and neural precursors in brain organoids derived from people with the mutation.

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New resource maps gene expression, regulation in neuron subtypes

by  /  1 July 2022

The catalog could help researchers understand the effects of autism-linked DNA variants that fall outside genes.

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June 2022

Unlocking the mitochondrial genome for autism research

by  /  1 June 2022

The DNA specific to mitochondria is difficult to access, but new methods place its secrets within reach.

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May 2022
Someone in a yellow shirt stands at a kitchen counter, watching a cooking video on a small tablet computer and following along.

Standard quality-of-life screener validated for autistic adults

by  /  24 May 2022

Researchers updated the tool’s scoring system to better align with the experiences of autistic people.

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3D rendering of a mouse brain showing axons coming from the prefrontal cortex in various colors.

New atlas maps neuronal wiring in mouse brain

by  /  3 May 2022

The ‘projectome’ charts axonal pathways between individual cells in the prefrontal cortex, a brain region implicated in autism.

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April 2022

Deep-learning tool tracks interacting animals in real time

by  /  27 April 2022

By coupling the tool — called SLEAP — with optogenetics, researchers can determine the neural circuits underlying social behaviors.

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Miniature microscope records thousands of neurons in moving mice

by  /  12 April 2022

The open-source device achieves subcellular resolution in a larger tissue volume than was possible with prior miniscopes, without impinging upon a mouse’s behavior.

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Open-source algorithm automates common marble-burying assay

by  /  1 April 2022

The machine-learning tool, which automatically counts how many marbles a mouse buries, appears to distinguish between hyperactivity and repetitive behaviors.

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March 2022

New MRI probe illuminates neuronal interactions

by  /  30 March 2022

The calcium-sensing instrument translates neuronal activity into signals that can be detected via functional magnetic resonance imaging (fMRI).

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