Emerging tools and techniques that may advance autism research.
A new spin on the classic CRISPR gene-editing tool can alter the genome’s chemical tags and suppress gene expression for months.
A new miniature iteration of a popular probe enables researchers to record activity at thousands of sites across the mouse brain and track the activity of individual neurons over months — providing long-term recording at an unprecedented scale.
An animated mouse reenacts common behavioral experiments and can be used to train algorithms that automatically track lab animals’ movements.
Researchers have defined a change in score on a popular autism rating scale that signifies a meaningful improvement in core traits. The measure could help scientists assess the effectiveness of autism treatments in clinical trials.
‘SNT’ helps researchers sift through microscope images to reconstruct and analyze neurons and their connections.
A technique that expands tissue before spotting and sequencing RNA — the molecular messenger for DNA — enables researchers to see where particular genes are expressed in cells.
The technique enables researchers to sequence the DNA of an intact cell, providing a unique view of the genome’s organization inside the nucleus.
An imaging approach that captures spheres of brain cells in three dimensions could illuminate processes in early brain development.
A new atlas profiles gene activity early on during development in the human fetal brain.
An expanding collection of websites compiles up-to-date information on the characteristics of people with mutations in genes linked to autism and other conditions.
Training community members to help families access care increases the likelihood that children from low-income and minority groups will obtain diagnostic evaluations.
