Emerging tools and techniques that may advance autism research.
Researchers have used stem cells to identify 801 neuronal genes that are preferentially expressed from either the maternal or paternal chromosome, according to a study published 30 August in PLoS One. Of these genes, 26 are linked to autism and 48 to schizophrenia.
Researchers have genetically engineered neurons to fluoresce in response to the calcium signals emitted when they fire, according to a study published 18 October in Neuron.
A new microscopy technique allows researchers to take high-resolution three-dimensional images of intact mouse brains.
The so-called ‘spiny mouse’ species has a gestational period twice as long as that of typical laboratory mice. This makes them good models for studying the link between prenatal exposure and autism risk, according to a study published 29 August in Brain, Behavior and Immunity.
A subset of questions on two behavioral screens can distinguish children with autism from those with other developmental disorders, according to a study published 23 August in Autism.
Researchers have induced stem cells to form three-dimensional clumps of neurons that resemble miniature brains, according to a study published 31 July in Proceedings of the National Academy of Sciences.
Researchers have developed an index that can predict the age of developing interneurons, which inhibit signals in the brain, according to a study published 24 August in PLoS One. They then used this measurement to show that interneurons are immature in autism brains.
Researchers have used a motion-capture system to show that children with autism do not rely on one side of the body more than the other when walking. Their findings were published in the 2012 issue of Autism Research Treatment.
A new device allows researchers to identify the precise source of an emitted brain signal measured in freely moving rats, according to a study published in the July issue of the Journal of Neurophysiology.
A new tool can sort through a population of mutant nematodes and identify those with altered neuronal connections, according to a study published 19 August in Nature Methods.
