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Spectrum: Autism Research News

Tag: gene networks

December 2014

Postmortem brains point to molecular signature of autism

by  /  22 December 2014

An analysis of genes expressed in the postmortem brains of people with autism has identified three molecular pathways linked to the disorder. The findings, published 10 December in Nature Communications, add to mounting evidence that the myriad causes of autism converge on common biological processes.

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November 2014

Different autism subtypes share same genetic signature

by  /  20 November 2014

A rare form of autism linked to a duplication of the 15q11-13 chromosomal region shares a molecular signature with more common forms of the disorder, suggests unpublished research presented yesterday at the 2014 Society for Neuroscience annual meeting in Washington, D.C.

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October 2014

Massive sequencing studies reveal key autism genes

by  /  29 October 2014

Analyzing the sequences of more than 20,000 people, researchers have unearthed the largest and most robust list of autism genes so far, they reported today in Nature.

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New resource catalogs impact of DNA variants on brain

by  /  22 October 2014

A new online database called Braineac details how variations in DNA sequence shape gene expression in the human brain.

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Database details neural gene interactions in developing mice

by  /  8 October 2014

A new online resource called MouseID Genes stores information about gene interactions in the developing mouse brain and spinal cord.

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July 2014

Molecular mechanisms: Patterns of DNA tags altered in autism

by  /  8 July 2014

Children with autism have atypical patterns of epigenetic modifications — chemical tags on DNA that influence gene expression, suggests a study published 29 May in PLOS Genetics.

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May 2014

Network of autism-linked proteins reveals new interactions

by  /  12 May 2014

Researchers have mapped interactions between hundreds of variants of proteins made from known autism risk genes, they reported 11 April in Nature Communications. The highly connected network reveals that autism genes tend to interact with each other and with many more partners than suspected.

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March 2014

Algorithm uncovers autism syndromes’ fingerprints

by  /  6 March 2014

An artificial-intelligence algorithm designed to analyze behavior has learned to recognize six genetic disorders associated with autism, according to a report published 11 February in Molecular Autism. The algorithm could be used to hone the search for autism’s genetic underpinnings.

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January 2014

Spontaneous and rare mutations are key in schizophrenia

by  /  30 January 2014

Spontaneous and rare mutations, particularly in genes related to networks that regulate neuronal connections, contribute a small but significant proportion of the risk for schizophrenia, report two large studies published online 22 January in Nature.

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Mounting evidence implicates cerebellum in autism

by  /  6 January 2014

Results from four studies published in the past year point to a role for the cerebellum in autism-related behaviors.

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