By analyzing the expression patterns of nine candidate genes for autism, researchers have identified a population of cells and a select time during fetal development that may be key to the disorder.
A new software algorithm called GAP measures the similarities in the function of more than 19,000 human protein-coding genes, according to a study published 14 March in BMC Systems Biology.
In his Directors’ Column, Alan Packer points out how a number of autism risk genes act on a common cellular pathway regulated by a single protein. What other similar convergent paths might be hiding in the literature? Let’s go on a treasure hunt.
Researchers have used protein and drug interaction networks to identify drugs approved for one disorder that may be useful for treating another, they reported 18 January in Bioinformation.
Researchers have created a network of various forms of many proteins linked to autism, revealing new molecular interactions that may play a role in the disorder. The unpublished work was presented in a poster last week at the Salk Institute, Fondation IPSEN and Nature Symposium on Biological Complexity in La Jolla, California.
Autworks, a new online tool, has data on almost 20,000 human genes linked to nearly 3,000 disorders. The tool, published 28 November in BMC Medical Genomics, creates gene-network maps for each disorder and highlights the overlap between them.
A new candidate gene for autism, CHD8, may account for up to 0.4 percent of cases of the disorder, according to research published today in Science. CHD8 is one of six genes identified that together may contribute to one percent of autism cases.
An in-depth analysis of tissue from a large number of autism brains eases some of the qualms about their use in research, according to a poster presented Monday at the 2012 Society for Neuroscience annual meeting in New Orleans.
An analysis of the expression patterns of 26 autism candidate genes identifies 4 whose expression coincides in a part of the cerebellum, according to research presented at the 2012 Society for Neuroscience annual meeting in New Orleans.
In a video interview, Simon Fisher discusses what language genes such as FOXP2 can reveal about the nature of autism.