Network analyses of gene expression patterns may point to key molecular pathways that autism alters and suggest new ways of treating the condition.

Criss-crossing the globe on a quest for unusual DNA, researchers have discovered a rare mutation that promises insights into both epilepsy and autism — and points to a treatment.

A new method harnesses the gene-editing system CRISPR to fine-tune gene expression in human cells.

Autism may stem from faulty feedback loops in the brain, like an air conditioning system gone awry.

Brian O’Roak has helped to steer some of the largest, most complex studies of autism genetics to date.

Researchers have uncovered 38 genes, including 9 autism candidates, that may fine-tune brain activity.

Our top 10 papers for this year, based on input from autism researchers, capture the full spectrum of findings — from molecular biology to large-scale epidemiology.

Patterns of gene expression in the brain vary dramatically between male and female mice — a finding that highlights the hazards of using only male mice to study complex disorders.

These short reports from our reporter, Jessica Wright, give you the inside scoop on developments at the 2015 American Society of Human Genetics Annual Meeting.

Autism researchers are sharpening their statistical tools to make sense of the growing pool of autism genes.