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Spectrum: Autism Research News

Tag: gene networks

March 2016

Questions for Richard Tsien: Taking apart autism’s machinery

by  /  22 March 2016

Autism may stem from faulty feedback loops in the brain, like an air conditioning system gone awry.

January 2016

Rising star: Brian O’Roak brings ‘A’ game to autism genetics

by  /  21 January 2016

Brian O’Roak has helped to steer some of the largest, most complex studies of autism genetics to date.


Some autism genes may act as control knobs for brain activity

by  /  4 January 2016

Researchers have uncovered 38 genes, including 9 autism candidates, that may fine-tune brain activity.

December 2015

Notable papers of 2015

by  /  22 December 2015

Our top 10 papers for this year, based on input from autism researchers, capture the full spectrum of findings — from molecular biology to large-scale epidemiology.

October 2015

Expression of mouse genes can vary by sex, strain

by  /  18 October 2015

Patterns of gene expression in the brain vary dramatically between male and female mice — a finding that highlights the hazards of using only male mice to study complex disorders.


New methods tighten ​net​ around autism genes

by  /  9 October 2015

Autism researchers are sharpening their statistical tools to make sense of the growing pool of autism genes.


Dispatches from ASHG 2015

by  /  9 October 2015

These short reports from our reporter, Jessica Wright, give you the inside scoop on developments at the 2015 American Society of Human Genetics Annual Meeting.

August 2015

Software forecasts effects of mysterious mutations

by  /  26 August 2015

A new computer program predicts the effects of mutations in regions of the genome that control gene expression. Researchers can use the tool, called DeepBind, to gauge whether autism-linked mutations might block the genetic landing strips for regulatory proteins.


Control centers for genes rife with autism-linked DNA blips

by  /  3 August 2015

DNA sequences called enhancers — which boost the expression of genes from within or outside them — are enriched for genetic variants linked to autism, suggests a new study. The finding may help researchers understand how variants outside genes contribute to autism.

July 2015

Method improves analysis of chemical tags that control genes

by  /  8 July 2015

A new strategy sharpens the analysis of chemical tags on the DNA-protein complexes that regulate gene expression. The method may help researchers decipher how gene expression goes awry in disorders such as autism.