Researchers have developed a computational technique that allows them to simultaneously use multiple types of information — including gene expression, ratings and associations — to identify candidate genes for a disorder. The unpublished results were presented Sunday at the 2011 Society for Neuroscience annual meeting in Washington, D.C.
Deleting the Rett syndrome gene in a subset of neurons, instead of throughout the body, dramatically lowers the number of genes that are dysregulated in those neurons, according to results presented in a poster session Saturday at the 2011 Society for Neuroscience annual meeting in Washington, D.C.
Individuals who have autism show distinct patterns of gene expression in neurological pathways compared with their unaffected siblings, according to unpublished work presented Saturday at the 2011 Society for Neuroscience annual meeting in Washington, D.C.
We’re headed to Washington, D.C. for the Society for Neuroscience annual meeting, and hope to make your lives a little bit easier by reporting on what matters to you.
We’re headed to Washington, D.C. for the Society for Neuroscience annual meeting, and hope to make your lives a little bit easier by reporting on what matters to you.
A protein linked to language development, FOXP2, regulates the autism candidate gene MET, according to a study published 10 August in the Journal of Neuroscience.
The protein missing in people with fragile X syndrome regulates the activity of more than 800 other proteins, including some key players in autism, according to a study published 22 July in Cell. Many of these autism-associated proteins cluster on either side of the synapse, the junction between neurons.
FOXP2, a gene tied to autism and language disorders, is needed for proper wiring of the developing brain, according to a study published 7 July in PLoS Genetics.
A new study calls into question the assumption that Rett syndrome is exclusively a neurodevelopmental disorder caused by the lack of a critical protein in utero.
Researchers have identified hundreds of previously unknown connections between proteins involved in autism spectrum disorders, according to a report published last week in Science Translational Medicine.