People with autism are twice as likely to carry alterations in genes that regulate the circadian clock, or the body’s sleep-wake cycle as those without the disorder. The findings may help explain why most children with autism have trouble with sleep.
Spectrum: Autism Research News
Tag: gene networks
Researchers have for the first time mapped gene expression in the rhesus macaque brain from birth through adulthood. The atlas illuminates the expression patterns of genes likely to be important in autism.
A new mathematical method confidently ranks genes based on their likely impact in a disorder. The approach may help researchers home in on important autism genes.
A new method for labeling cell lines and checking their quality could improve the validity of study results.
A new technique allows researchers to trace the location and measure expression levels of hundreds of genes in individual cells. The method, described 9 April in Science, could reveal networks of genes with relevance to autism.
Watch the complete replay of Kathryn Roeder’s webinar discussing how powerful statistical tools can yield insight into the genetic risk for autism.
Small pieces of DNA within genes, dubbed ‘microexons,’ are abnormally regulated in people with autism, suggests a study of postmortem brains.