Researchers have used gene expression data to create a map of the layers within the neocortex, a brain region involved in sensory perception, motor control and language, of rhesus macaques. The results were published 22 March in Neuron.
Spectrum: Autism Research News
Tag: gene networks
Researchers have mapped networks of genes expressed at the same time and place in the brain and shown that rare and common autism-linked mutations are likely to function in the same pathways. The results were published 8 March in PLoS Genetics.
Simulating neuronal development in culture with cells derived from human brain tissue offers a new way to study the function of autism-linked genes, according to research published in the February issue of Molecular Psychiatry.
A mathematical approach called ‘NEW biology,’ or network-enabled wisdom biology, aims to solve one of the biggest problems in disease research: isolating the key factors that drive diseases from a glut of information.
Researchers have charted the expression of more than 15,000 brain genes across 15 stages of development, spanning from 4 weeks post-conception to more than 60 years of age, they reported 27 October in Nature.
The molecular soldiers of the immune system may contribute to many cases of autism, according to a diverse array of studies published in the past few months.
In the brains of some individuals with autism, chemical changes to histones, proteins entwined with DNA, tend to show up near genes linked to the disorder, according to a study published 7 November in the Archives of General Psychiatry.