Now that genetic studies have implicated several hundred genes in autism, researchers are turning their attention to where and when in the healthy young brain these genes are expressed. The first two studies to tackle these questions appear today in Cell.
Spectrum: Autism Research News
Tag: gene networks
A new online database lists the likely RNA-binding sites of more than 8,000 proteins from 289 species. Researchers debuted the resource in the 11 July issue of Nature.
Although thousands of candidate genes are linked to autism, many function together in just a few common pathways, according to a network analysis published in the June issue of PLoS Genetics.
RORA, an autism candidate gene, encodes a protein that binds more than 2,500 other genes and alters the expression of some of those genes, according to a study published 22 May in Molecular Autism.
By analyzing the expression patterns of nine candidate genes for autism, researchers have identified a population of cells and a select time during fetal development that may be key to the disorder.