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Tag: epigenetics

November 2013
News / Toolbox

Neurons made from teeth may aid autism research

by  /  13 November 2013

Cells extracted from baby teeth, which fall out on their own, may be better suited than skin cells for making induced neurons to use in autism research, suggests a study published 3 October in PLoS One.

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October 2013
News

Gene screen reveals altered chemical tags in autism brains

by  /  14 October 2013

One of the largest genome-wide screens of methyl tags in postmortem brains has found that people with autism have three unique regions of methylation — chemical modifications that affect gene expression. The results were reported 3 September in Molecular Psychiatry.

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September 2013
News / Toolbox

New method uses light to toggle gene expression

by  /  25 September 2013

Researchers have modified optogenetics — a technique that activates neurons in mouse brains with beams of light — to toggle a gene on or off. They reported the advance 22 August in Nature.

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News

Molecular mechanisms: Study shows Angelman drug’s actions

by  /  24 September 2013

Researchers have uncovered the mechanism by which a candidate drug for Angelman syndrome activates UBE3A, the gene that is silenced in the syndrome, according to a study published 20 August in the Proceedings of the National Academy of Sciences.

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August 2013
Opinion

Fertility factor

by  /  6 August 2013

The simplest form of in vitro fertilization does not increase the risk for autism or intellectual disability, but the effect of other fertility treatments is still unclear, according to two large Scandinavian studies published in July.
 

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News

Multinational resource compiles autism risk factors

by  /  5 August 2013

A new database pools health registry data from seven countries, dramatically boosting sample sizes for epidemiological studies of autism.

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July 2013
News

Map of methylation mirrors changes in brain development

by  /  22 July 2013

Researchers have debuted the most comprehensive map to date showing how the suite of methyl tags on the DNA of brain cells changes across the genome over a lifetime. The map, published 4 July in Science, suggests that shifting patterns of methylation may guide key periods of brain development.

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June 2013
News

Study uncovers molecular targets of autism-linked RORA gene

by  /  6 June 2013

RORA, an autism candidate gene, encodes a protein that binds more than 2,500 other genes and alters the expression of some of those genes, according to a study published 22 May in Molecular Autism.

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May 2013
News

Twin study finds epigenetic imprint of autism traits

by  /  16 May 2013

Epigenetics, or the chemical markings on DNA that affect gene expression, plays a role in some cases of autism, according to a study of 50 identical twins published 23 April in Molecular Psychiatry.

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News

Molecular mechanisms: Maternal infection modifies histones

by  /  7 May 2013

Infection during pregnancy may alter the chemical tags that are added to histones, proteins that form a spool for DNA, according to a study published 9 February in Brain, Behavior and Immunity. Drugs that target these tags may treat neuropsychiatric disorders, the researchers say.

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