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Tag: epigenetics

October 2011
News

Later-born children at higher risk for autism

by  /  24 October 2011

In families that have more than one child with autism, the middle children, particularly those born second, have a higher risk of developing autism than other children in the family, according to a study published 19 October in PLoS One. In families that have only one child with autism, however, risk of the disorder rises with each additional birth, the study found.

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News

Fast-evolving gene is key player in brain development

by  /  14 October 2011

A gene that changed rapidly after the human genome diverged from that of Neanderthals plays a critical role in brain development, according to unpublished results presented Thursday at the International Congress of Human Genetics in Montreal, Canada.

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News

Clinical research: Parents share some autism traits

by  /  4 October 2011

Individuals who have multiple children with autism have more severe social and communication deficits than either controls or those who have only one child with autism.

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September 2011
News

Molecular mechanisms: Maternal stress affects male mice

by  /  30 September 2011

The male offspring of mice subjected to stress during pregnancy can transmit the effects to their own male pups.

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News

Brain activity triggers widespread epigenetic changes

by  /  26 September 2011

Methylation marks were thought to be permanent features of the genome, but a new study challenges that idea.

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News / Toolbox

Reference set for Prader-Willi, Angelman syndromes debuts

by  /  14 September 2011

Researchers have developed standard genetic reference samples that clinicians can use to diagnose Angelman and Prader-Willi syndromes, two disorders associated with the same chromosomal region.

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News

New mutations spike in offspring of older fathers

by  /  12 September 2011

The offspring of older male mice are 16 times more likely to harbor a spontaneous copy number variation — a deletion or duplication of genetic material — than are the offspring of young males, according to a new study.

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August 2011
News

Attention deficit, autism share genetic risk factors

by  /  22 August 2011

Some of the same genetic risk factors may underlie both autism and attention deficit hyperactivity disorder, according to a study published 10 August in Science Translational Medicine.

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July 2011
News

Methylation map of neurons points to autism-related genes

by  /  25 July 2011

Large-scale patterns of methylation throughout the genome affect the expression of many autism-related genes and may contribute to the disorder’s development, according to a study published online Friday in Genome Research. The study is among the first to look at genome-wide patterns of methylation in brain cells.

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News

Experts critique statistics, conclusion of autism twin study

by  /  14 July 2011

A new study of twins proposes the controversial claim that environmental influences during early development are just as, if not more, important than genetics. But the findings are not substantially different from those of previous twin studies, however, and some experts are critical of the study’s statistics.

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