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Tag: epigenetics

July 2011
Opinion / Viewpoint

Studying infant sibs of children with autism spectrum disorder

by  /  5 July 2011

Studying the infant siblings of children who have autism to identify early signs of the disorder is expected to have enormous impact on the field from a clinical and a basic science standpoint, says psychologist Karen Dobkins.

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June 2011
News

Clinical research: Prenatal vitamins lower risk of autism

by  /  24 June 2011

Taking prenatal vitamins for three months before conception and four weeks after could lower the risk of having a child with autism, particularly for women who carry certain genetic variants, according to a study published in the July issue of Epidemiology.

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News

Molecular mechanisms: Metabolic changes increase risk of autism

by  /  8 June 2011

Children with autism have fewer DNA modifications that regulate gene expression compared with healthy siblings and controls, and show evidence of DNA damage, according to a study published 26 April in the Journal of Autism and Developmental Disorders.

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May 2011
News

Family sequencing study boosts two-hit model of autism

by  /  15 May 2011

A new analysis of children with autism and their unaffected parents provides the best evidence to date that mutations in multiple genes may work together to cause autism and related disorders.

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Opinion / Viewpoint

Promises and limitations of mouse models of autism

by  /  10 May 2011

Good mouse models of autism, and accurate tests to assay their phenotypes, are key to both narrowing down a cause and developing effective treatments, argues expert Jacqueline Crawley.

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April 2011
News

Genetics: Identical twins not so similar

by  /  20 April 2011

Identical twins can be genetically different, which could explain why they do not always share disorders such as schizophrenia or autism, according to a study published in March in PLoS One.

2 Comments
News

Maternal stress alters behavior of generations

by  /  18 April 2011

Early trauma alters both behavior and gene expression in three generations of mice, suggesting that epigenetic changes may contribute to ‘hidden heritability’ in neuropsychiatric disorders.

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March 2011
News

New candidate gene may explain male bias of autism

by  /  24 March 2011

A gene that regulates the conversion of testosterone to estrogen in the brain could help explain why males are more susceptible to autism than are females, according to a study published in PLoS One in February.

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January 2011
News

Risk of autism spikes for children of older men

by  /  28 January 2011

A man’s risk of fathering a child with autism begins to rise at age 30 and significantly increases after age 50, according to a report published online 30 November in Molecular Psychiatry.

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News

New drug rescues function in fragile X syndrome

by  /  20 January 2011

A new drug appears to relieve symptoms of fragile X syndrome by blocking the over-production of a key protein in a subset of people with the disorder, according to a 6 January study in Science Translational Medicine.

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