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Tag: inhibitory signaling

November 2011
News

Neurexins present only in select neurons

by  /  15 November 2011

Neurexins, autism-linked proteins that organize synapses, the junctions between neurons, function in only a subset of cells in the brain, according to data presented in a poster Monday at the 2011 Society for Neuroscience annual meeting in Washington, D.C.

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News

Subset of Rett gene’s targets may lead to the disorder

by  /  14 November 2011

Deleting the Rett syndrome gene in a subset of neurons, instead of throughout the body, dramatically lowers the number of genes that are dysregulated in those neurons, according to results presented in a poster session Saturday at the 2011 Society for Neuroscience annual meeting in Washington, D.C.

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News

Vision problems in Rett syndrome could serve as biomarker

by  /  13 November 2011

Mice missing the Rett syndrome gene MeCP2 show a gradual decline in vision, and too much inhibitory signaling in the visual cortex, according to unpublished research presented Thursday in Washington, D.C.

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News

Molecular mechanisms: MeCP2 may modify DNA structure

by  /  9 November 2011

The Rett syndrome gene MeCP2 may subtly regulate the expression of genes across the genome by altering DNA structure.

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October 2011
News / Toolbox

Researchers engineer light-responsive strains of mice

by  /  5 October 2011

Researchers have engineered four new mouse lines that each show activation of a different subset of neurons in response to a blue light.

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September 2011
News / Toolbox

Three-dimensional re-creation reveals dendrite shapes

by  /  28 September 2011

Researchers have created detailed three-dimensional reconstructions of the numerous complex branches of dendrites, the signal-receiving ends of neurons.

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News

Cognition and behavior: Probiotics alleviate anxiety in mice

by  /  20 September 2011

Probiotic bacteria alleviate stress in healthy mice and modify the expression of receptors for a chemical messenger that inhibits signaling in the brain.

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News

Molecular mechanisms: Dopamine implicated in Rett syndrome

by  /  13 September 2011

Loss of MeCP2, the Rett syndrome gene, in neurons that release the chemical messenger dopamine may lead to the motor deficits associated with the syndrome.

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August 2011
News

Genetics: Gene variants can predict autism severity

by  /  19 August 2011

Children with autism who carry a certain variant of a protein involved in inhibitory signaling have more severe symptoms than those with another variant of the same gene, according to a study published 24 July in the Journal of Autism and Developmental Disorders.

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News

Optogenetics study boosts signal imbalance theory of autism

by  /  8 August 2011

By zapping mouse brains with blue and yellow light beams, scientists have manipulated the animals’ social behaviors and bolstered a popular theory of what causes autism.

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