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Tag: inhibitory signaling

December 2009
News

Chemical messenger variant found in families with autism

by  /  16 December 2009

Scientists have for the first time found direct evidence that defects in the GABA receptor sometimes give rise to autism, according to research published 24 November in Molecular Psychiatry.

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November 2009
News

Loss of inhibitory neurons marks autism mouse models

by  /  24 November 2009

Autism may be the result of faulty wiring that occurs during early brain development, according to two independent studies that looked at the origins of circuit disruption.

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October 2009
News

Mounting evidence links language pathway to autism

by  /  26 October 2009

A pathway involved in language development is increasingly proving to be important in autism, suggest a series of new studies on cellular and behavioral aspects of the disorder.

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News

MeCP2 loss ups inhibitory signaling

by  /  21 October 2009

Selectively disrupting an autism-related gene in cultured human neurons causes a dramatic imbalance of excitation and inhibition in cell signaling, according to unpublished results presented today at the Society for Neuroscience meeting in Chicago.

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News

Language gene linked to interneuron growth

by  /  20 October 2009

A gene tied to autism and language impairment is crucial for the early development and migration of inhibitory interneurons, according to research presented Monday at the Society for Neuroscience meeting in Chicago.

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November 2008
News

Creating stem cells to study autism

by  /  18 November 2008

A team of scientists is reprogramming adult stem cells generated from tiny skin samples of people with autism to form nerve cells, creating a powerful research tool for the disorder.

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February 2008
News

Mouse models for autism debut

by  /  19 February 2008

Two research groups have achieved an elusive goal: producing mouse models that show distinct social and behavioral abnormalities reminiscent of autism.

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January 2008
News / Profiles

Josh Huang: In dogged pursuit of autism’s off switch

by  /  3 January 2008

In 1982, Josh Huang was an impressionable young biology undergraduate at Shanghaiʼs FuDan University. Like some of his fellow Chinese students, he knew he wanted to be a neuroscientist, but with limited access to scientific journals, had no idea which big questions were then at the forefront of research.

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December 2007
News / Profiles

Gordon Fishell: Oracle’s gift to autism

by  /  7 December 2007

Along with answering fundamental questions about mammalian brain organization, watching interneurons’ “handshake” with other brain cells is the key to understanding autism, says Gordon Fishell.

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