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Tag: inhibitory signaling

April 2014

Low-dose sedative eases autism symptoms in mice

by  /  3 April 2014

The equivalent of one-tenth of a single pill of the anxiety drug clonazepam alleviates many autism-like behaviors in a mouse model of the disorder, according to a study published 19 March in Neuron.

Opinion / Viewpoint

The cerebellum’s surprisingly evolved role in autism

by  /  1 April 2014

Thought until recently to only coordinate motor skills, the cerebellum is involved in diverse cognitive functions such as language and social interaction, and may play a role in autism, says Emanuel DiCicco-Bloom.

February 2014

Drug calms overly excitable brains in autism rodent models

by  /  10 February 2014

The blood pressure drug bumetanide normalizes a deficit in brain activity in two rodent models of autism, according to a study published last week in Science. The study hints at a mechanism underlying the drug’s benefits for people with autism.

January 2014
Multimedia / Webinars

Michael Merzenich discusses plasticity in autism

29 January 2014

Watch the complete replay of Michael Merzenich discussing how the brain’s ability to change with experience may lead to new treatments for autism.

December 2013
Opinion / Viewpoint

Understanding contradictory connectivity reports in autism

by ,  /  10 December 2013

Studies at the level of neural circuits are needed to better understand the importance of both increased and decreased connectivity between different regions in the autism brain, say John Rubenstein and Vikaas Sohal.

1 Comment
November 2013
News / Toolbox

Neurons made directly from skin cells model autism mutations

by  /  27 November 2013

Skin cells taken from mice with an autism-linked mutation and transformed directly into neurons have the same properties as neurons from the brains of these mice. The study, published 8 October in Proceedings of the National Academy of Sciences, validates an efficient technique to study disease-linked mutations.

Opinion / Viewpoint

More or less connected in autism, compared to what?

by  /  19 November 2013

Emerging findings in children with autism are showing both hyperconnectivity and underconnectivity in different regions and circuits throughout the brain.


New imaging method details brain abnormalities in mice

by  /  14 November 2013

A new imaging technique that can assemble finely detailed pictures of an individual mouse’s brain in less than a day is being used to explore mouse models of autism. Data from the first two models were presented Wednesday at the 2013 Society for Neuroscience annual meeting in San Diego.


Gut problems in autism may stem from neuronal connections

by  /  12 November 2013

Researchers have shown for the first time that glitches in a gene expressed at junctions between neurons can cause gut problems in mice. The unpublished results were presented Tuesday at the 2013 Society for Neuroscience annual meeting in San Diego.


Activity in cerebellum silences seizures in mice

by  /  10 November 2013

Activating cells in the cerebellum, a brain region usually associated with movement, eliminates seizures in a mouse strain that normally has hundreds of seizures a day, according to results presented Saturday at the 2013 Society for Neuroscience annual meeting in San Diego.