Tag: inhibitory signaling

March 2018
Week of FebruaryFeb
26th
2018
News / Spotted

Marketing oils for autism; pruning principle matures; mouse manual and more

by  /  2 March 2018

Autism parents fall for the marketing of essential oils, the pruning hypothesis of brain development matures, and an online manual classifies mouse behavior.

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February 2018
colorful hands marking a path
News

Twist on gene-editing tool may speed studies of gene function

by  /  21 February 2018

Researchers have repurposed the gene-editing tool CRISPR to dial down a gene’s activity in select subtypes of neurons in mice.

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January 2018
Mice lacking one copy of MEF2C have fewer neurons (red and green, right) in the hippocampus than controls do (left).
News

Modified Alzheimer’s drug may treat some forms of autism

by  /  18 January 2018

A fusion of two existing drugs alleviates autism-like features in a mouse model of the condition.

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black rat and white rat
News

Anxiety drug reverses problems in mice with autism mutation

by  /  4 January 2018

A widely used treatment for anxiety can eliminate some of the cognitive and social problems seen in mice missing a copy of ARID1B, a gene associated with autism.

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November 2017
black mice exiting hole
News

Learning shows sex bias in mice with mutation tied to autism

by  /  23 November 2017

Male mice with a genetic variant tied to autism may have learning difficulties that females with the variant do not.

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magnetic stimulation of human brain
News

Magnetic stimulation bares imbalance of activity in fragile X brains

by  /  14 November 2017

Researchers have used transcranial magnetic stimulation to show that people with fragile X syndrome have weak ‘inhibitory’ signals, those that dampen neuronal activity in the brain.

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lab mice
News

Fragile X behaviors may stem from gene’s loss in specific cells

by  /  13 November 2017

Deleting FMR1, the gene mutated in fragile X syndrome, in subsets of mouse neurons leads to distinct features of the condition.

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Mice that lack UBE3A only in their inhibitory neurons are particularly susceptible to seizures.
News

Gene therapy technique prevents seizures in Angelman mice

by  /  12 November 2017

Introducing the gene UBE3A into neurons that dampen brain activity prevents seizures in a mouse model of Angelman syndrome.

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Stimulating inhibitory neurons in a visual brain region prevents monkeys from focusing on a line on a computer screen.
News

Light-based method controls inhibitory neurons in macaques

by  /  12 November 2017

Researchers have used light to manipulate neurons that dampen brain activity in rhesus macaques.

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October 2017
Microscope image of neuronal injections in brain.
News

Two drugs ease features of autism syndromes in mice

by  /  11 October 2017

Drugs that block certain brain enzymes could help treat two conditions associated with autism.

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