Tag: inhibitory signaling

August 2019
News

Drugs that calm ‘touch neurons’ may ease autism traits

by  /  8 August 2019

An experimental drug that muffles the activity of neurons in the skin moderates heightened reactions to touch in six mouse models of autism.

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May 2019
News

The signaling imbalance theory of autism, explained

by  /  1 May 2019

The signaling imbalance theory holds that the brains of autistic people are hyper-excitable because of either excess neuronal activity or weak brakes on that activity.

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February 2019
Close up of mouse shows whiskers
News

Four sets of mice call popular autism theory into question

by  /  25 February 2019

An analysis of four mouse models negates certain assumptions underlying the signaling imbalance theory of autism.

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January 2019
Rat neurons
News

Rat model of autism shows unusual brain growth at birth

by  /  30 January 2019

The brains of rats exposed in utero to the seizure drug valproate show a significant increase in brain size around the time of birth.

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December 2018
News

Massive analysis refines map of autism’s genetic roots

by  /  19 December 2018

The largest genetic analysis of postmortem brain tissue to date has yielded maps of when and where genes related to autism are turned on and off throughout life.

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November 2018
Delicate network of neurons and synapses.
News

Webbing around neurons altered in autism mouse models

by  /  8 November 2018

Lattice-like structures that surround neurons may be overly abundant — or scarce — in brain regions of three autism mouse models.

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Two hands hold two pills, one red and one blue.
News

Drug duo delivers brain, behavioral benefits for fragile X syndrome

by  /  8 November 2018

Administering a cholesterol drug alongside an antibiotic eases atypical behavior and restores the signaling balance in the brains of people with fragile X syndrome.

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Chandelier cells send their signals through fibers arranged in vertical columns that are reminiscent of the candles in a chandelier.
News

Chandelier cells may sprout few branches in autism brains

by  /  7 November 2018

Specialized neurons called chandelier cells, which dampen brain signals, make unusually few connections in the brains of people with autism.

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Artistic interpretation of a neuron in the hippocampus.
News

Subset of neurons may underlie brain’s response to experience

by  /  7 November 2018

Experiences may shape the human brain by altering neurons that boost brain activity.

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Neurons glow green in mice brain.
News

Loss of autism gene alters landscape of inhibitory brain signals

by  /  6 November 2018

Mice lacking one copy of a leading autism gene have hyperexcitable brains and problems with learning and memory.

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