Mutations in GABRB3, a brain receptor linked to autism, are prevalent in severe childhood epilepsy, according to a study published 12 September in Nature.
Newborn mice with an autism-linked mutation in neuroligin-3, which stabilizes junctions between neurons, have abnormal brain chemistry, according to a study published 4 June in Frontiers in Cellular Neuroscience.
The mutation that causes tuberous sclerosis complex, an autism-related disorder, may disable calming signals in the brain, leading to hyperactive neurons, according to a study published 8 May in Neuron.
Two different autism-linked mutations in the same gene implicate the endocannabinoid system, which regulates appetite, mood and memory, in autism, according to a study published 8 May in Neuron.
Prenatal exposure of rats to the epilepsy drug valproic acid leads to behavioral and brain features that resemble autism, in males more than in females, according to a study published in the March issue of the Journal of Neurochemistry.
Loss of one copy of 22q11.2 — a chromosomal region linked to schizophrenia and autism — shifts the location of neurons that inhibit brain signals, according to a study published 6 November in Proceedings of the National Academy of Sciences.