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Tag: inhibitory signaling

August 2012
News

Genetics: Rare epilepsy syndromes share autism mutations

by  /  22 August 2012

Individuals with either of two rare forms of epilepsy have duplications or deletions that encompass genes implicated in autism and language impairment, according to a study published 27 June in Epilepsia.

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News / Toolbox

Choice of light-sensitive channel alters inhibitory signals

by  /  1 August 2012

An innovative technique that uses waves of light to silence brain signaling in live animals can affect subsequent neuronal signals, according to a study published 24 June in Nature Neuroscience.

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July 2012
Opinion / Viewpoint

Targeting brain microcircuits may help treat autism

by  /  10 July 2012

Understanding the function of neuronal circuits, specifically microcircuits in the prefrontal cortex and elsewhere in the brain, will play a major role in translating research findings into new autism treatments, says Vikaas Sohal.

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News

Angelman mice show impaired inhibition of brain signals

by  /  2 July 2012

Mice lacking a functional copy of UBE3A, the gene missing or mutated in people with the rare developmental disorder Angelman syndrome, show less inhibitory activity than controls do, according to research published 7 June in Neuron.

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June 2012
News

Genetics: Analysis identifies new autism candidate regions

by  /  19 June 2012

An analysis of large duplications and deletions of DNA has identified new candidate genes for autism in pathways linked to the disorder. The results were published 22 May in Human Molecular Genetics.

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May 2012
News / Toolbox

New technique helps locate source of brain imaging signals

by  /  16 May 2012

Combining functional magnetic resonance imaging of rat brains with a technique that uses light to detect neuronal activity can help researchers hone in on the source of the activity, according to a study published 6 May in Nature Methods.

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News

Genetics: Study further implicates rare CNVs in autism

by  /  2 May 2012

Individuals with autism are more likely than controls to have small, rare duplications or deletions of stretches of DNA in genes that play a role in dampening signals in the brain, according to a study published 2 April in Molecular Autism.

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April 2012
News / Toolbox

Chili pepper protein can alter behavior of mice

by  /  18 April 2012

By manipulating the location of a protein that detects capsaicin, the molecule responsible for the burn in hot chili peppers, researchers can activate subpopulations of neurons and alter the behavior of mice. The results were published 20 March in Nature Communications.

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News / Toolbox

Researchers map gene expression in the monkey brain

by  /  4 April 2012

Researchers have used gene expression data to create a map of the layers within the neocortex, a brain region involved in sensory perception, motor control and language, of rhesus macaques. The results were published 22 March in Neuron.

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March 2012
News

Molecular mechanisms: Extra MeCP2 affects brain signaling

by  /  30 March 2012

Mice with an extra copy of MeCP2, the Rett syndrome gene, have impaired signaling between neurons in the hippocampus, a brain region that plays an important role in memory, according to a study published 29 February in The Journal of Neuroscience.

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