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Emerging tools and techniques that may advance autism research.

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March 2014

Reference strains aid genetic testing for Rett syndrome

by  /  26 March 2014

Researchers have established a set of commercially available cell lines that can help gauge the quality of tests for Rett syndrome, they reported in the March issue of the Journal of Molecular Diagnostics.

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New technique finds mutant cells in a haystack

by  /  19 March 2014

Researchers have developed a method to isolate a single mutant cell from thousands of others, they reported in the March issue of Nature Methods.

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New molecules help researchers orchestrate brain activity

by  /  12 March 2014

Using newly discovered molecules from algae, researchers can control the activity of two families of neurons in a single mouse or fly, they reported 9 February in Nature Methods.

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Come-hither rat cry could measure social interest

by  /  5 March 2014

When navigating a maze, rats move toward happy rodent sounds and away from those signaling alarm, according to a review published 4 February in the Journal of Neuroscience Methods. The method could be used to assay social behavior in rodent models of autism.

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February 2014

Gene expression implicates inhibitory neurons in autism

by  /  26 February 2014

By matching the genes expressed in particular cell types with those linked to a disorder, researchers may be able to identify the cell types implicated in the disorder, they report in a study published 22 January in the Journal of Neuroscience. They use this method to link interneurons and immune cells to autism.

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Virtual joystick shows preference for personal space

by  /  19 February 2014

Children with autism are likely to keep more distance between themselves and a welcoming avatar than controls do in a virtual reality setup, suggesting that they derive less pleasure from social situations, according to a study published 17 January in the Journal of Autism and Developmental Disorders.

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Induced neuron cell line resembles immature, healthy neurons

by  /  12 February 2014

A commercially available line of neurons generated from induced stem cells would serve as a good control for autism research, according to a study published 16 January in Psychopharmacology.

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Automated tool records behavior of autism mouse models

by  /  5 February 2014

A new tracking system automatically logs and scores mouse behavior as well as a human observer does, according to a paper published 31 December 2013 in Journal of Neuroscience Methods.

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January 2014

Eye-tracker charts gaze of children with autism

by  /  29 January 2014

A lightweight eye-tracking system allows researchers to record the shifts in gaze that naturally occur during playtime, reports a study published 20 November in Frontiers in Psychology.

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Symptom database may find patterns in complex disorders

by  /  22 January 2014

The Human Phenotype Ontology project has assembled more than 10,000 standardized terms for human diseases and the symptoms that accompany them, researchers reported 1 January in Nucleic Acids Research.

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