Skip to main content
NEWS /
OPINION /

Toolbox

Emerging tools and techniques that may advance autism research.

Previous articles

December 2012

Network tool highlights links between genes and disorders

by  /  19 December 2012

Autworks, a new online tool, has data on almost 20,000 human genes linked to nearly 3,000 disorders. The tool, published 28 November in BMC Medical Genomics, creates gene-network maps for each disorder and highlights the overlap between them.

0 Comments

Precocious piglets may model neurological disorders

by  /  12 December 2012

The brains of newborn pigs are similar in shape and mature at the same rate as those of human infants. That makes piglets a good model for studying neurological disorders, according to a study published in the November issue of The Journal of Nutrition.

0 Comments

Software tool homes in on disease-linked mutations

by  /  5 December 2012

By combining pedigree information with sequencing data, a new software tool helps focus on genetic variants likely to be responsible for disease, researchers reported 10 October in Bioinformatics.

0 Comments
November 2012

New technique prepares mouse brains for mapping

by  /  28 November 2012

Researchers have developed a method to fix and stain intact mouse brains for electron microscopy, according to a study published 21 October in Nature Methods. The technique allows them to trace the paths of neurons as they project across the brain.

0 Comments

Female mice model late onset of Rett syndrome

by  /  21 November 2012

Female mice of two different genetic backgrounds consistently model the behavioral features of Rett syndrome, according to a study published 9 October in Human Molecular Genetics. Although Rett syndrome presents almost entirely in girls, researchers have thus far relied mostly on male mice to model the disorder.

0 Comments

Brain atlas maps gene expression in three dimensions

by  /  14 November 2012

Researchers have charted patterns of gene expression in a three-dimensional representation of the human brain. The results, published 20 September in Nature, show that different brain regions have distinct molecular and functional roles.

0 Comments

Virtual brain suggests neural connections form randomly

by  /  7 November 2012

Researchers are assembling a virtual reconstruction of the brain by piecing together simulations of thousands of neurons, they reported 16 October in the Proceedings of the National Academy of Sciences. They used this model to show that most junctions between neurons form randomly and not as the result of chemical signals.

1 Comment
October 2012

Stem cells reveal genes that have parental bias

by  /  31 October 2012

Researchers have used stem cells to identify 801 neuronal genes that are preferentially expressed from either the maternal or paternal chromosome, according to a study published 30 August in PLoS One. Of these genes, 26 are linked to autism and 48 to schizophrenia. 

0 Comments

Technique follows calcium trail to track changes in signaling

by  /  24 October 2012

Researchers have genetically engineered neurons to fluoresce in response to the calcium signals emitted when they fire, according to a study published 18 October in Neuron.

0 Comments

New technique takes sharp look at whole mouse brains

by  /  17 October 2012

A new microscopy technique allows researchers to take high-resolution three-dimensional images of intact mouse brains.

0 Comments

Browse Articles by Topic

Click on the arrows or swipe to view topics.
  • Genes
    Genes
  • The Brain
    The Brain
  • Diagnosis
    Diagnosis
  • Signs and Symptoms
    Signs & Symptoms
  • Treatments
    Treatments
  • Environment
    Environment
  • Science and Society
    Science & Society