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April 2012
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Researchers map gene expression in the monkey brain

by  /  4 April 2012

Researchers have used gene expression data to create a map of the layers within the neocortex, a brain region involved in sensory perception, motor control and language, of rhesus macaques. The results were published 22 March in Neuron.

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March 2012
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Researchers make neurons from blood cells

by  /  28 March 2012

Researchers have generated neurons from the blood cells of individuals with autism, according to a study published 7 March in Neuroscience Letters.

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Online tool can predict effects of genetic variants

by  /  21 March 2012

Researchers have developed a tool that can predict whether DNA mutations that change a single base pair are likely to alter RNA splicing, a process that modifies the sequence of mRNA, the genetic message that codes for protein. The results were published 10 February in Bioinformatics.

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Autism mutations lead to scores of symptoms in rodents

by  /  14 March 2012

Mutations in more than 100 autism-associated genes lead to shared neurobiological deficits in mice, including alterations in the shape of their brains and changes to the electrical properties of neurons, according to a study published 20 February in Molecular Autism.

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Fruit fly reference helps link genes to traits

by  /  7 March 2012

Researchers have generated and sequenced almost 200 different strains of fruit flies, a widely used model organism, according to a study published 8 February in Nature. The resource they created, called the Drosophila Genetic Reference Panel, will enable researchers to link genetic variants with aspects of fly biology and behavior.

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February 2012
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MRI devices for children reduce head motion in scanner

by  /  29 February 2012

Researchers have developed functional magnetic imaging devices that are optimized to fit children’s heads, according to a study published in the December issue of Magnetic Resonance in Medicine. These tools increase the quality of the data and deter head motion, which research suggests can lead to spurious results.

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Study charts methylation patterns in developing brain

by  /  22 February 2012

Researchers have charted patterns of DNA methylation — a chemical alteration to DNA that modifies gene expression — in the planning center of the brain from before birth to old age. The results were published 10 February in The American Journal of Human Genetics.

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Researchers chart 3D structure of fruit fly chromosomes

by  /  15 February 2012

A new study reveals the three-dimensional structure of fruit fly chromosomes, which groups together active and inactive genes. The results were published 3 February in Cell.

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Microscope reveals nanoscale detail in live mouse brains

by  /  8 February 2012

A new microscope allows researchers to capture the movement of tiny signal-receiving branches in the brains of adult mice at the nanoscale level. The results were published 3 February in Science.

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New machine takes rapid, reliable pictures of brains

by  /  1 February 2012

An automated instrument can reconstruct fluorescently labeled mouse brains in less than a day, researchers reported 15 January in Nature Methods.

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