New resource catalogs impact of DNA variants on brain
A new online database called Braineac details how variations in DNA sequence shape gene expression in the human brain.
Emerging tools and techniques that may advance autism research.
A new online database called Braineac details how variations in DNA sequence shape gene expression in the human brain.
Combining analysis of large deletions or duplications in the genome with sequences from protein-coding regions can identify new syndromes, as well as the mutations that cause those disorders, according to a report published 14 September in Nature Genetics.
A new online resource called MouseID Genes stores information about gene interactions in the developing mouse brain and spinal cord.
CRISPR, the genetic tool that cuts and pastes DNA, can eliminate specific proteins at the points of connection between neurons. The method, described 3 September in Neuron, could help researchers determine the role of those proteins in brain signaling.
A method for measuring myelin, the protective sheath around neurons, indicates that there is less of it in the brains of people with autism than in those of controls.
Bioengineers have built a donut-shaped scaffold that supports the growth of brain-like tissue, they reported 11 August.
A new algorithm accurately detects large DNA insertions and deletions in the protein-coding regions of the genome.
Researchers have put together a set of strategies and computer programs to identify mutations in mitochondrial DNA that contribute to disorders such as autism.
A new technique helps researchers trace the nerve fibers that connect brain regions by revealing how the fibers physically relate to curves and folds on the brain’s surface. The method was described 8 July in Medical Image Analysis.
An adaptation of a test for facial recognition makes it easier to chart children’s ability to remember faces.