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Spectrum: Autism Research News

Tag: hippocampus

February 2013

Cognition and behavior: Neurobeachin loss mimics autism

by  /  8 February 2013

Mice missing one copy of neurobeachin, an autism-linked gene that fine-tunes signals at neuronal junctions, show autism-like behaviors, according to a study set to be published in the March issue of Neurobiology of Disease.

January 2013

Alzheimer’s drug aids autism mouse model

by  /  23 January 2013

Memantine, a drug used to treat Alzheimer’s disease, can reverse autism-like features in mice lacking one copy of the MEF2C gene, according to a poster presented last week at the Salk Institute, Fondation IPSEN and Nature Symposium on Biological Complexity in La Jolla, California.

December 2012

Autism-linked protein sets pace for brain development

by  /  10 December 2012

Mutations in SYNGAP1, which are associated with severe intellectual disability and an increased risk of autism, do damage by speeding up the rate at which neuronal connections mature, according to a mouse study published 9 November in Cell.

October 2012

Technique follows calcium trail to track changes in signaling

by  /  24 October 2012

Researchers have genetically engineered neurons to fluoresce in response to the calcium signals emitted when they fire, according to a study published 18 October in Neuron.


Prenatal antibodies boost brain stem cells in mice

by  /  18 October 2012

Prenatal exposure to antibodies collected from the mothers of children with autism boosts stem cell proliferation in the brains of mice, according to two studies presented at the 2012 Society for Neuroscience annual meeting in New Orleans.


Autism-linked gene influences brain volume

by  /  16 October 2012

People with a certain variant in RBFOX1, a gene linked to autism risk, have a smaller temporal lobe than those with other variants, according to research presented Monday at the 2012 Society for Neuroscience annual meeting in New Orleans.


‘Spiny mice’ model risk of autism from maternal infection

by  /  10 October 2012

The so-called ‘spiny mouse’ species has a gestational period twice as long as that of typical laboratory mice. This makes them good models for studying the link between prenatal exposure and autism risk, according to a study published 29 August in Brain, Behavior and Immunity.

September 2012

Molecular mechanisms: Drug corrects excitable mouse brains

by  /  5 September 2012

A compound called baclofen restores the balance between different types of brain signals and alleviates autism-like behaviors in mice, according to a study published 17 July in Translational Psychiatry. A similar drug called arbaclofen is in clinical trials as a treatment for autism and fragile X syndrome.

July 2012

Expression data links gene candidates to autism

by  /  11 July 2012

Identifying genetic variants that affect the expression of other genes can enhance traditional gene association analyses and highlight candidate risk factors for autism, according to a study published 16 May in Molecular Autism.

June 2012

SHANK2 mouse models show opposite brain signaling

by  /  25 June 2012

Two new strains of mice carrying different mutations in the SHANK2 gene show similar autism-like behaviors but opposing effects on brain signaling, according to two independent studies published 14 June in Nature.