The SHANK family of proteins, some of which are strong autism candidates, work together to facilitate brain signaling, according to unpublished results presented yesterday at the 2014 Society for Neuroscience annual meeting in Washington, D.C.
Spectrum: Autism Research News
Mice with an extra copy of the autism-linked gene UBE3A show abnormal social behavior after experiencing recurrent seizures. The findings, presented Tuesday at the Autism Consortium Research Symposium in Boston, provide one possible explanation for why seizures and autism often go hand in hand.
A new online database called Braineac details how variations in DNA sequence shape gene expression in the human brain.
Male mice that carry a specific mutation in the autism-linked PTEN gene have enlarged brains and show heightened interest in other mice, according to a study published 7 February in Human Molecular Genetics.
Removing the fragile X syndrome gene from two brain regions in mice leads to signaling defects but does not produce behavioral deficits, according to a study published in the February issue of Autism Research.
When exposed to irritating noises or images, children with autism show hypersensitivity in brain regions that process sensory information and emotions, according to a study published in November in the Journal of the American Academy of Child and Adolescent Psychiatry.