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Tag: epigenetics

December 2010
News

Genetics: Gene that controls methylation linked to autism

by  /  17 December 2010

A gene involved in epigenetics — regulation of gene expression by modifying DNA, but without altering the sequence — is associated with autism in families that have only one child with the disorder, according to a study published in November.

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November 2010
News

Autism symptoms more severe in younger siblings

by  /  17 November 2010

In families with more than one child diagnosed with autism, younger siblings appear to be more severely affected by the disorder, according to new data presented Tuesday at the Society for Neuroscience annual meeting in San Diego.

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October 2010
News

Linkage study reveals parent-of-origin effects in autism

by  /  29 October 2010

The first genome-wide linkage analysis of more than 1,200 families has identified regions implicated in autism as originating from either the paternal or maternal copies of chromosomes.

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Opinion

Speed trap

by  /  13 October 2010

New DNA tests for fragile X syndrome are quick, but also raise ethical questions: they pick up abnormalities in some babies who won’t develop symptoms until adulthood, if at all.

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Opinion

Science by zodiac

by  /  5 October 2010

Research has hinted that the season of a child’s birth may play some role in his or her risk of developing various neuropsychiatric disorders. But it’s the season of conception that really matters, a new study suggests.

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August 2010
News

Brain’s adaptability begins at single synapse

by  /  10 August 2010

Researchers have uncovered an important molecular piece of a learning mechanism that occurs at the junction between neurons. The findings, which may help understand how the brain is disrupted in disorders such as autism, appear in the 24 June issue of Neuron.

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News

Fragile X models give clues to stem cell programming

by  /  9 August 2010

Not all stem cells are created equal, a string of new studies suggests: adult cells that are reprogrammed into stem cells carry chemical remnants of the tissue from which they originate, making them distinct from embryonic stem cells. These differences may have important implications for studying fragile X syndrome and other diseases that arise from epigenetic glitches.

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July 2010
News

Deep sequencing questions role of imprinted genes in autism

by  /  8 July 2010

The mouse brain has more than 1,300 regions for which the copy from one parent is expressed more often than the one from the other parent, according to two studies published today in Science. These so-called imprinted genes have been proposed to cause some cases of autism, but the researchers say their findings do not support that theory.

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May 2010
Opinion

Granny’s genes

by  /  19 May 2010

The older a grandmother was when she bore her grandchild’s mother, the greater the child’s risk of autism, according to a study published last month in PLoS One.

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News

New technique maps methylated DNA

by  /  14 May 2010

A new technique can simultaneously sequence DNA and pinpoint some of the chemical modifications that turn genes on or off, according to a report published 9 May in Nature Methods. In particular, the technique reveals methyl groups bound to DNA bases.

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