The ‘projectome’ charts axonal pathways between individual cells in the prefrontal cortex, a brain region implicated in autism.

By coupling the tool — called SLEAP — with optogenetics, researchers can determine the neural circuits underlying social behaviors.

The open-source device achieves subcellular resolution in a larger tissue volume than was possible with prior miniscopes, without impinging upon a mouse’s behavior.

The machine-learning tool, which automatically counts how many marbles a mouse buries, appears to distinguish between hyperactivity and repetitive behaviors.

The calcium-sensing instrument translates neuronal activity into signals that can be detected via functional magnetic resonance imaging (fMRI).

The ability to conduct large-scale screening in human neurons could accelerate the discovery of autism treatments.

The new animal line could accelerate the discovery of gene-activating therapies for the autism-linked condition Rett syndrome.

A modified version of a probe commonly used in animals detected neuronal activity across different cortical layers in three people undergoing brain surgery.

By automatically quantifying gait and posture in videos of mice, a new machine-learning tool could accelerate research on how autism-linked mutations or drug treatments affect motor skills.

A new viral variant can deliver genes exclusively to the brain, overcoming a key hurdle in treating neurological conditions using gene therapy.