Silenced X chromosome genes reawaken in new mouse model
The new animal line could accelerate the discovery of gene-activating therapies for the autism-linked condition Rett syndrome.
Emerging tools and techniques that may advance autism research.
The new animal line could accelerate the discovery of gene-activating therapies for the autism-linked condition Rett syndrome.
A modified version of a probe commonly used in animals detected neuronal activity across different cortical layers in three people undergoing brain surgery.
By automatically quantifying gait and posture in videos of mice, a new machine-learning tool could accelerate research on how autism-linked mutations or drug treatments affect motor skills.
A new viral variant can deliver genes exclusively to the brain, overcoming a key hurdle in treating neurological conditions using gene therapy.
Mice that express a fluorescent synaptic receptor reveal the interactions between neurons in unprecedented detail.
New software can automatically identify and quantify mouse social behavior from videos, saving researchers time.
An online database called NyuWa catalogs genetic variations among nearly 3,000 individuals and provides a comprehensive reference genome for the Han people.
Two new methods make it possible to delete long sections of the genome, expanding the reach of CRISPR gene editing.
The new technique can record hundreds of thousands of neurons firing nearly simultaneously across big swaths of brain tissue in living mice.
The app relies on artificial intelligence and could help researchers standardize studies of pupil differences in autistic people and in mouse models of autism.