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Emerging tools and techniques that may advance autism research.

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March 2022

Silenced X chromosome genes reawaken in new mouse model

by  /  3 March 2022

The new animal line could accelerate the discovery of gene-activating therapies for the autism-linked condition Rett syndrome.

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February 2022

Probe captures neuronal conversations in people

by  /  9 February 2022

A modified version of a probe commonly used in animals detected neuronal activity across different cortical layers in three people undergoing brain surgery.

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Software automatically measures mouse's gait and posture by tracking various points on the mouse's body.

Algorithm spots subtle gait changes in autism mouse models

by  /  4 February 2022

By automatically quantifying gait and posture in videos of mice, a new machine-learning tool could accelerate research on how autism-linked mutations or drug treatments affect motor skills.

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January 2022

Neuron-specific virus overcomes barriers to brain-related gene therapy

by  /  14 January 2022

A new viral variant can deliver genes exclusively to the brain, overcoming a key hurdle in treating neurological conditions using gene therapy.

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New method spotlights synaptic plasticity in living mice

by  /  5 January 2022

Mice that express a fluorescent synaptic receptor reveal the interactions between neurons in unprecedented detail.

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December 2021

Artificial intelligence system categorizes interactions between mice

by  /  17 December 2021

New software can automatically identify and quantify mouse social behavior from videos, saving researchers time.

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Nighttime crowded Shanghai street scene with illumination from electric and neon signs.

New resource tracks genetic variations in Han Chinese populations

by  /  9 December 2021

An online database called NyuWa catalogs genetic variations among nearly 3,000 individuals and provides a comprehensive reference genome for the Han people.

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November 2021

New gene-editing tools delete long stretches of DNA

by  /  17 November 2021

Two new methods make it possible to delete long sections of the genome, expanding the reach of CRISPR gene editing.

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October 2021

‘Light beads’ method images activity across the mouse brain

by  /  12 October 2021

The new technique can record hundreds of thousands of neurons firing nearly simultaneously across big swaths of brain tissue in living mice.

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Annimation of eye tracking application following the pupil in a man's eye.

Web app tracks pupil size in people, mice

by  /  8 October 2021

The app relies on artificial intelligence and could help researchers standardize studies of pupil differences in autistic people and in mouse models of autism.

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