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Emerging tools and techniques that may advance autism research.

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April 2018
scientific illustration of protein mutations
News / Toolbox

Web-based tools reveal mutations’ effects on proteins

by  /  27 April 2018

Two new online resources help researchers predict how mutations alter protein structure.

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genetic code sequences
News / Toolbox

Map of DNA variation identifies key genetic regions

by  /  20 April 2018

A new analysis of the genomes of more than 11,000 people reveals regions that have few mutations, indicating they have important functions.

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scans of a mouse brain with highlighted regions
News / Toolbox

Active neurons emit visible glow from depths of animal brains

by  /  13 April 2018

Modified versions of molecules found in fireflies make brain cells glow so brightly they are visible from outside the body.

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A silicon nanowire touches the membrane of a rat neuron.
News / Toolbox

Silicon nanowires stimulate neurons with light

by  /  6 April 2018

Microscopic silicon wires could enable scientists to excite neurons with light without first inserting genes into them.

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March 2018
Tiny particles (blue), along with light-sensitive proteins (green) and light, excite neurons (red) in a reward region of the mouse brain.
News / Toolbox

Tiny particles safely stimulate neurons buried in brain

by  /  30 March 2018

A new technology that converts near-infrared light to visible light can manipulate neurons nestled deep in the brain.

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water droplets contain and concentrate the materials needed to synthesize genes.
News / Toolbox

New tools speed genome assembly, tests of gene function

by  /  23 March 2018

Two new techniques could help reveal the molecular basis of conditions such as autism.

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honeycomb shape with arrows shows the pattern of activity of rats in the maze
News / Toolbox

‘Honeycomb’ maze elevates testing of rodents’ spatial skills

by  /  16 March 2018

A maze comprising 37 hexagonal platforms may offer researchers an accurate measure of rodents’ ability to navigate their surroundings.

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boy lying down on the floor touching a metal object
News / Toolbox

New instrument could assess effects of behavioral treatments

by  /  9 March 2018

A new questionnaire assesses the frequency and severity of various behaviors in children with autism.

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A section of loosely packed DNA points to genes that a cell is actively turning into proteins.
News / Toolbox

Map of DNA structure marks autism risk regions

by  /  2 March 2018

A new map of DNA structure highlights sequences that regulate the formation of neurons in the developing brain.

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February 2018
More than 4,000 types of brain cells show distinct gene expression patterns.
News / Toolbox

Map of gene expression gives new clues to brain development

by  /  23 February 2018

A new map that analyzes gene expression one cell at a time shows how various cell types mature and form the brain’s distinctive structures.

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