Repurposed electronics lens spies neurons across entire mouse brain
When combined with tissue-inflation methods, the microscope can image axons without the need for tissue slicing, the researchers say.
Emerging tools and techniques that may advance autism research.
When combined with tissue-inflation methods, the microscope can image axons without the need for tissue slicing, the researchers say.
The framework, inspired by the polygenic risk score, considers the cumulative effect of neuronal connections.
The gene-editing advances make it easier to target specific tissues in mice and detect off-target effects.
The approach provides an “off-the-shelf” way for researchers to compare oxytocin function across species, the team says.
The new resource aims to aid reproducibility in imaging research.
Genes exert their strongest influence on the brain in the first half of gestation — a key window for autism and other neurodevelopmental conditions.
The Gender Self-Report could help autism researchers include more gender-diverse people across a range of ages and neurotypes in their work.
The work identifies new varieties and may help researchers develop tools to genetically target specific classes of cells.
The tool connects to electrodes implanted in people with epilepsy or other brain conditions and can monitor and regulate neurons during everyday activities.
The finding calls into question differences between autistic and non-autistic people on a decades-old theory-of-mind test involving interacting geometric shapes.