Science & Society

National Institutes of Health director Francis Collins talks about the agency’s upcoming plans for “beefing up” autism research, including more than $100 million each year in grants for the field.

Some of the most profound mysteries of human nature relate to how we communicate and interact with each other. Matthew Belmonte, assistant professor of human development at Cornell University, talks about how studying people with autism can help understand these aspects in healthy people.

It’s that time of year again — fall foliage, plump pumpkins and, if you’re a neuroscientist, the mad, mobbed scenes at the Society for Neuroscience (SFN) annual meeting.

A team of British researchers has garnered some of the first genetic evidence supporting their theory that sex hormones play a role in the development of autism.

A common variant of a gene called CACNA1G — which makes a channel that helps regulate calcium flow between cells — may increase the risk of developing autism, according to research published in Molecular Psychiatry.

In the spring of 2002, as a new graduate student at the University of Washington, Raphael Bernier was charged with introducing his advisor, Geraldine Dawson, before her lecture to a room of about 40 people from the psychology department. To Dawson’s astonishment, Bernier sang his introduction to the tune of On Top of Old Smokey. “[It was] a pretty gutsy thing for a first-year student to do,” Dawson says.

Research on mouse models published in the past year is paving the way to reversing the symptoms of some autism-related disorders, National Institute Health directors told a packed room of 80 reporters at the morning at the Society for Neuroscience conference.

Brain tissue from individuals with autism is rare, to say the least: of the 30,000 samples in the National Institutes of Healthʼs Brain and Tissue Bank for Developmental Disorders, for instance, only 30 are from individuals diagnosed with autism.

Even as I type this, thousands of neuroscientists are descending on Washington D.C. for an annual event that is almost beyond description. An estimated 36,000 people are expected to attend Neuroscience 2008, this yearʼs meeting of the Society for Neuroscience, hobnob, listen to lectures, present posters and down drinks at the many social events.

Sitting on a sofa in his office at the Yale Child Study Center, Ami Klin plays a movie clip on a tiny laptop. The clip stars a younger Klin, with larger glasses but the same easy smile, vying for the attention of a young girl with autism. His face inches from hers, he speaks in a warm, animated voice. But the girl never looks from the toy blocks in her hands. Suddenly, she spots an orange M&M in the far corner of the room and scoots after it.