Boys with autism who carry rare, spontaneous mutations have lower intelligence quotients and more severe symptoms than do those who may have inherited the disorder. The finding, published 21 October in the Proceedings of the National Academy of Sciences, hints at two classes of autism risk with varying severity.
Spectrum: Autism Research News
Science & Society
From funding decisions to scientific fraud, a wide range of societal factors shape autism research.
A new online database called Braineac details how variations in DNA sequence shape gene expression in the human brain.
Researchers have sequenced the whole genomes of 1,000 people with autism and their parents, they announced yesterday at the American Society of Human Genetics Annual Meeting in San Diego. These sequences, and another 1,000 that are on the way, will eventually be freely available online.
Having an enlarged head in early childhood is not a reliable marker of autism, according to two new studies that tracked changes in head and body size in children over time.
Combining analysis of large deletions or duplications in the genome with sequences from protein-coding regions can identify new syndromes, as well as the mutations that cause those disorders, according to a report published 14 September in Nature Genetics.
Two new studies, both by reputable teams of researchers, report that there are no detectable differences between boys and girls with autism.
Restricted behaviors in autism represent a genetic link with inattention and hyperactivity in attention deficit hyperactivity disorder, say Tinca Polderman and Henrik Larsson.